Why does the Rf of 2,4-DTBP change dramatically compared with 2,6-DTBP with a change in solvent system?
2007-01-17 15:41:54 · 2 answers · asked by Anonymous in Science & Mathematics ➔ Chemistry
Hexane is the non polar component of this mixture so increasing its percentage will decrease the polarity of the mixture. As to your second question, you need to explain the acronym DTPB.
2007-01-18 13:48:49 · answer #1 · answered by Bullwinkle Moose 6 · 0⤊ 0⤋
Typical TLC plates are silica. And your system indicates the compound is quite polar. So what I would do it switch to 90:10 CHCl3-Methanol, with a drop of formic acid added. If it still doesn't migrate, increase the amount of methanol. The formic acid will make the spot tighter. Yes, there are many proposed systems, often ternary, but chloroform-methanol combinations are convenient and simple.
2016-05-24 02:20:31 · answer #2 · answered by Anonymous · 0⤊ 0⤋