A TATA box (also called Goldberg-Hogness box) is a DNA sequence (Cis-regulatory element) found in the promoter region of most genes (it is considered to be the core promoter sequence) in eukaryotes.
It is normally bound by the TATA Binding Protein (TBP) in the process of transcription, which melts the DNA, and bends it through 90°. The AT-rich sequence facilitates easy melting.
The TATA box is usually found as the binding site of RNA polymerase II. The transcription factor TFIID binds to the TATA box, followed by TFIIA binding to the upstream part TFIID. TFIIB can then bind to the downstream part of TFIID. The polymerase can then recognise this multi-protein complex and bind to it, along with various other transcription factors such as TFIIF, TFIIE and TFIIH. Transcription is then initiated, and the polymerase moves along the DNA strand, leaving TFIID and TFIIA bound to the TATA box. These can then facilitate the binding of additional RNA polymerase II molecules.
Thus TATA box is used to melt DNA, which facilitates easy replication and analysis.
2007-01-10 15:59:59
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answer #1
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answered by simply 1
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Tata Dna
2016-12-16 16:01:21
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answer #2
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answered by ? 4
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TATA boxes do not function in DNA replication. They are important promoters for transcription, but have no role in replicaiton.
2007-01-11 01:21:53
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answer #3
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answered by floundering penguins 5
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From what I know the TATA box is a promoter found in eucaryotic DNA recognized by certain proteins in the process of transcription (the making of mRNA)...., not in replication of DNA...
If it is in transcription, then the TATA box is the signal to start with this process
2007-01-10 15:56:34
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answer #4
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answered by ♥βετ§¥♥ 2
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2016-12-16 06:27:50
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answer #5
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answered by ? 4
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Its an initiation site.
2007-01-10 15:53:25
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answer #6
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answered by ihavenoidea 3
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thats where the whole replication engine starts
http://en.wikipedia.org/wiki/TATA_box
2007-01-10 15:52:29
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answer #7
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answered by t_roy_e 3
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