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I need help on these 3 Hardy Weinberg Problem..can someone go through the steps of each one to show how you got the answer? I'm totally confused!

4. A population of mice shows a recessive trait of white fur 49% of the time. What is the frequency of the dominant allele?

5. In a midwest town with a population of 9375, 75% of the townsfolk show the dominant trait of free earlobes. How many people in this should be heterozygous for free earlobes?

7. the frequency of stillbirths homozygous for a recessive lethal gene is about 1 in 25000. What is the proportion of the carriers (heterozygous) in that population?

2007-01-10 12:01:56 · 2 answers · asked by hellokid 1 in Science & Mathematics Biology

2 answers

Problem 4: Hardy-Weinberg says that p^2 + 2pq + q^2 = 1 when p represents the dominant allele and q is the recessive allele. The white mice are the q^2 because they must have two of the recessive alleles each.

q^2 = 0.49 Changed 49% to a decimal.
q = 0.7 Because 0.7 squared is 0.49.

Start substituting in the equation to find out what p equals.

p^2 + 2pq + q^2 = 1
p^2 + 2p(0.7) + 0.49 = 1
p^2 + 1.4 p - 0.51 = 0 Simplified and put into standard form.

Solve using the quadratic formula or factor and solve.
(p + 0.17)(p - 0.3) = 0
p = -0.17 or p = 0.3 (answer must be positive)

Either way you get p = 0.3 which is the frequency of the dominant allele.
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Problem 5: If 75% show free earlobes, then 25% show attached earlobes. p^2 + 2pq = 0.75 q^2 = 0.25 (so q = 0.5)
p + q = 1 This is an underlying principle of H-W
p + 0.5 = 1
p = 0.5

2 pq = 2(0.5)(0.5) = 0.5 So half of the population is heterozygous.

The population is 9375. Half of 9375 = 4687 or 4688 people are heterozygous.
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Problem 7: q^2 is the frequency of homozgous recessive (1/25000 in this problem, which is 0.00004).

q^2 = 0.00004, so q = 0.0063
p + q = 1, so p = 1 - 0.0063 = 0.9937

According to equation p^2 + 2pq + q^2 = 1
Proportion of the carriers = 2 pq
Substitute figures from above for p and q
2 pq = 2(0.0063)(0.9937) = 0.0125 which is just about 1 out of 800 since I had a bit of rounding along the way.

Answer 1/800 or 0.0125 of the population is heterozygous.

2007-01-10 13:15:44 · answer #1 · answered by ecolink 7 · 0 0

optimistically, this can help you % out all of those on your guy or woman. do no longer ignore that: p=frequency of dominant allele q=frequency of recessive allele p+q=a million so if you're given both one in each of both, you would possibly want to be particular the alternative. this substances with the allele frequencies. (A +a)/finished # of alleles=a million p squared=homozyous dominant pq=heterzygous q rectangular = homozygous recessive p squared +pq+q squared=a million (this allow you to realize each the genotypes and phenotypes) (AA+Aa+aa)/volume of organisms=a million a million represents the completed inhabitants. each allele may favor to be recessive or dominant so both may favor to operate as plenty because of the very reality the completed alleles=a million. each organism may favor to be homozygous dom, heterozygous, or homozygous recessive, so all of those may favor to operate as plenty because of the very reality the completed organisms=a million.

2016-12-28 15:56:48 · answer #2 · answered by ? 3 · 0 0

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