Where can I find an image of a chromosome that shows lactose intolerance?

Question

I tryed google images.....any ideas or suggestions?!

Answer 1

From http://www.emedicine.com/ped/topic1270.htm
The gene for lactase is located on chromosome 2. While the DNA in individuals with low and high levels of lactase activity does not differ, differences do exist in messenger RNA (mRNA), suggesting that the primary regulation of this enzyme occurs during translation.

This means that most people do not have a genetic mutation on lactase gene, but more likely the gene gets transcribed less. See http://www.foodnavigator.com/news/ng.asp?id=42796-scientists-identify-lactose for a mutation study.

The particular gene itself (on the chromosome) will not be visible unless you want to draw it out yourself! If you want to know the sequence of the normal lactase gene, see http://www.ebi.ac.uk/cgi-bin/dbfetch?db=emblcds&id=AAA51819

If you want to see the normal protein, see http://modbase.compbio.ucsf.edu/modbase-cgi/model_details.cgi?queryfile=1168217517_2203&searchmode=default&displaymode=moddetail&referer=yes&snpflag=

Answer 2

At the bottom of this paragraph, last paragraph in the document are diagrams:

We'll see that this hemiacetal (anomeric) carbon is where most of the reactions of glucose take place, but first, let's look at some other important monosaccharides (sugars held together by only carbon-carbon bonds). Fructose (a keto-hexose) is an isomer of glucose and is found in corn syrup, fruits and honey. It too can form a hemiacetal, but its has a five-membered ring. Galactose is a diastereomer of glucose, with the mirror image relationship at the carbon above the bottom chiral one. It is a component of lactose, the primary disaccharide (next time) of milk. This small change at one carbon requires a different enzyme for digestion than the one which works for glucose. Persons who lack enough of this enzyme can't digest galactose, which ferments in the large intestine with the production of gas, cramps and diarrhea. This is call lactose intolerance.

Ribose is an aldopentose. Along with its close relative, deoxyribose, it is important in RNA and DNA. In both cases, the hemiacetal form has a five membered ring. See Diagram at First Link

Answer 3

Try looking up antibodies. IgA for intolerances.