Denaturation is the alteration of a protein shape through some form of external stress (for example, by applying heat, acid or alkali), in such a way that it will no longer be able to carry out its cellular function. Denatured proteins can exhibit a wide range of characteristics, from loss of solubility to communal aggregation.
Proteins are very long strands of amino acids linked together in specific sequences. A protein is created by ribosomes that "read" codons in the gene and assemble the requisite amino acid combination from the genetic instruction, in a process known as translation. The newly created protein strand then undergoes post-translational modification in which additional atoms or molecules are added, for example copper, zinc, iron. Once this post-translational modification process has been completed, the protein begins to fold (spontaneously, and sometimes with enzymatic assistance), curling up on itself so that hydrophobic elements of the protein are buried deep inside the structure and hydrophilic elements end up on the outside. The final shape of a protein determines how it interacts with its environment.
2007-01-06 18:13:30
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answer #1
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answered by Asking for a social outcry 1
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< denaturalize denatured alcohol >
de·na·ture (d-nchr) KEY
TRANSITIVE VERB:
de·na·tured , de·na·tur·ing , de·na·tures
To change the nature or natural qualities of.
To render unfit to eat or drink without destroying usefulness in other applications, especially to add methanol to (ethyl alcohol).
Biochemistry
To cause the tertiary structure of (a protein) to unfold, as with heat, alkali, or acid, so that some of its original properties, especially its biological activity, are diminished or eliminated.
To cause the paired strands of (double-stranded DNA) to separate into individual single strands.
Physics To add nonfissionable matter to (fissionable material) so as to prevent use in an atomic weapon.
2007-01-07 02:13:58
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answer #2
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answered by Jenn 2
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if the enzyme is denatured, it means that it can no longer do its function. the active site has been deformed so that the enzyme cannot break down the specific substances. causes would be extreme temperatures and pH or the active site is blocked by poison such as cynide
2007-01-07 02:19:20
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answer #3
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answered by pigley 4
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how many times do you want this question answerd ?? i thought twice is enough, look up previous if youre serious
2007-01-07 02:14:28
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answer #4
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answered by da rinse mode 4
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read about it at
http://www.learnnc.org/lessons/BertWartski8222002227
2007-01-07 02:15:14
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answer #5
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answered by Piguy 4
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