how does the structure of urate oxidase look like?

Question

a picture would be greatly appreciated, or even a link to where i could see one.....thanks!!

Answer 1

http://www.umass.edu/microbio/chime/pe_beta/pe/protexpl/frntdoor.htm

Go to this site and use the PDB code 1R4U (code for urate oxidase)
You might need to download the Chime software, but it's free and there's instructions. After you do that, you'll have a full 3D diagram and just about any analysis tools you'll need

Answer 2

While you can look for pictures on google images, the most reputable source I can think of is NCBI's structural database. You'll need to download a program to view the structure (http://www.ncbi.nlm.nih.gov/Structure/CN3D/cn3d.shtml). It will allow you to rotate the protein, view the sequence, and highlight amino acid residues. Search NCBI's structural database (http://www.ncbi.nlm.nih.gov/Structure/MMDB/mmdb.shtml) for urate oxidase to see the different options. They have the enzyme complexed with different small molecules so that you can see how it binds to them. In some cases, they are only depicting the monomer, and in others, they show you how the monomers associate together. This result (http://www.ncbi.nlm.nih.gov/Structure/mmdb/mmdbsrv.cgi?form=6&db=t&Dopt=s&uid=26511) is the enzyme by itself. To zoom in, hold control while dragging your mouse to the right.