Red Blood Cell, White Blood Cell, Platelet, Plasma.
Red Blood Cell contains hemoglobin which is important for transporting oxygen.
White blood cells help fight foreign invasion.
Platelets are important in blood clotting.
Plasma is the liquid in our body that helps transport stuffs.
2006-12-27 17:05:22
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answer #1
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answered by PIPI B 4
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plasma, erythrocytes (red blood cells), leukocytes (white blood cells), and platelets are the four major components. Plasma is the liquid component of blood or the substance in which the other components move to other parts of the body. It makes up about 70% of the blood volume and contains a lot of proteins involved in transport, immune response, and structure. Red blood cells are what makes the blood red and carry oxygen to the other parts of the body with the aid of the protein hemoglobin. White blood cells are primarly responsible for immune responses. There are different types of leukocytes with different functions~anything from fighting a virus to creating an allergic response. Platelets are responsible for repairing damaged area by clotting the blood.
2006-12-28 01:51:27
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answer #2
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answered by dally1025 3
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Where do blood components come from?
Blood components are made from blood collected from volunteer blood donors. Blood donation programs exist to allow blood to be donated by a patient for themselves, by anonymous donors or, in some situations, by someone specified by the recipient.
Blood may be processed into any of these various blood components:
Whole blood
Whole blood contains red blood cells and plasma. Whole blood is often used for open-heart surgery and may also be used for exchange transfusions (complete replacement of a baby's blood) in newborn babies with hemolytic disease of the newborn. This product is otherwise not commonly used.
Packed red blood cells
Red blood cells carry oxygen to the tissues. Packed red blood cells have had most of the plasma removed from the whole blood. Packed cells are usually given into a vein over 2-4 hours to replace the red cells lost through bleeding, hemolysis (destruction of the red blood cells), or decreased production of red cells by the bone marrow. The decreased production of cells may be due to bone marrow failure, cancer involving the marrow, or the effect of chemotherapy drugs used to treat a cancer.
Fresh frozen plasma
Contains clotting factors - Fresh frozen plasma is plasma which was frozen and stored shortly after it was obtained from the blood donor. Fresh frozen plasma contains many clotting factors and is often used alone or with cryoprecipitate to replace the low levels of clotting factors. It is usually given into a vein over one to two hours.
Platelets
Blood cell fragments which help blood clot - Platelets are the cell fragments which prevent or stop bleeding or bruising by physically plugging the hole in the blood vessel. Platelets are usually given into a vein over a few minutes to an hour. If a patient's bone marrow is not producing platelets, then platelet transfusions are usually needed once or twice a week, or even more often. Platelets may also be given when a patient's platelets are not functioning properly due to medicines, illness or mechanical damage (such as from an artificial heart valve).
Cryoprecipitate
Cryoprecipitate is the part of the blood which contains only certain clotting factors such as factor VIII (deficient in hemophilia A), von Willebrand factor, and fibrinogen. Currently, cryoprecipitate is usually given only as a source of fibrinogen (necessary for forming a clot). Some patients with certain types of hemophilia or patients who lack fibrinogen may receive cryoprecipitate to treat their clotting defect. Also, severely ill patients may develop an abnormal clotting condition known as DIC (disseminated intravascular coagulation), which can cause a decrease in the body's clotting factors and result in severe bleeding. Cryoprecipitate along with fresh frozen plasma (see above) may be given to help replace the clotting factors that are low. Cryoprecipitate is usually given over just a few minutes to an hour into a vein.
Granulocytes
Cells which help fight infections - Granulocytes, also called neutrophils, are the cells which help fight off bacterial or fungal infections. Granulocytes are very occasionally given to help fight off severe infections in patients who have very low numbers of granulocytes in the blood and have not responded to medications. Most often granulocytes are given daily for five days or until the patient's granulocyte count returns to a level which allows the patient to fight the infection on his or her own. Granulocytes are usually infused into a vein over one to two hours.
What are the risks associated with blood transfusions?
Sometimes there are adverse reactions that occur with the use of a blood component. Most of these reactions are not common and can usually be easily managed. If an adverse reaction occurs, alternative methods to solve the problem may be used.
Immune mediated adverse reactions can occur if a patient's immune system reacts to the blood component or if the immune cells in the blood component react to the patient's cells or fluids. These reactions are not common. They may include allergic reactions, an anaphylactic reaction, the development of red blood cell or platelet antibodies which shorten the lifespan of these cells in the bloodstream, transfusion-related damage to the lung tissue (TRALI), a delayed destruction of red blood cells, and graft versus host disease (GVHD).
There are several possible non-immune mediated adverse reactions. Most of them are rare. These may include bleeding problems, fluid overload, reaction from extra potassium in the blood component, tingling of the hands and lips caused by lowered blood calcium level, and an overload of iron in the body tissues which can occur in patients who receive more than 100 units of red blood cell transfusions.
An infection could occur from the use of a blood component that contains bacteria, a virus (for example, cytomegalovirus (CMV), Hepatitis B and C, or HIV) or a parasite. Infections from transfusions are rare since screening blood donors and testing and filtering blood has made the blood supply in the United States the safest that it has ever been. The risk of contracting Hepatitis B can be further reduced with a vaccine.
Learn more about these risks by speaking with your health care team, by reading details of these adverse reactions and by visiting recommended web sites.
What are some of the symptoms that can occur after a blood transfusion?
Symptoms to watch for include:
Fever over 100.6°F (38°C) orally, blood pressure changes
Chills, headache, nausea, vomiting, diarrhea or back pain
Dark-colored urine, hives, itching, wheezing or shortness of breath or difficulty breathing
Swelling of feet or ankles, or a cough that was not present before the transfusion
Delayed reactions - in rare cases, a delayed reaction can occur three to 10 days following a transfusion of red blood cells. Call your child's doctor if your child develops a fever or becomes pale or jaundiced (yellow color in skin and whites of eyes) three to 10 days after a blood transfusion.
If your child should develop symptoms after receiving a blood product, call your nurse or doctor right away.
Are there any alternatives to the transfusion of a blood component?
There are other possible choices in some situations. Your health care team can identify which ones may be used, depending on your child's condition. These alternatives include the following:
Drugs are available which can stimulate the bone marrow to make more red blood cells (erythropoietin), white blood cells (granulocyte-colony stimulating factor), and platelets (interleukin-11). Newer agents are being developed.
Bleeding problems can be treated by giving specific clotting factors such as Coagulation Factor VIII or IX concentrates, or by giving drugs which decrease the risk of bleeding in the mouth and throat (Amicar) or increase the level of certain coagulation factors (DDAVP). If the bleeding is caused by too much heparin in the body, this can be reversed by protamine sulfate.
Some patients who have surgery can have their own blood stored before the surgery. After the surgery, they get their own blood back (an autologous unit). Other patients may have their blood which is lost during surgery given back to them (intraoperative salvage procedure).
You may also ask a specific donor to give blood for the transfusion, if the donor is compatible and the blood is free of infectious agents. Experience has shown that these directed donor units are not any safer than blood from a regular volunteer blood donor. Some patients can tolerate a low hemoglobin level for a few days after surgery and build back their own blood supply by taking extra iron. Some patients, for religious reasons, specifically try to avoid blood product transfusions. The above alternatives are available to them. In the future, a blood substitute may become an option for such patients.
2006-12-28 02:18:24
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answer #7
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answered by wierdos!!! 4
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