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If B cells are created inside the bone marrow where is T cells made? and what does each white blood cell do, do they do the same thing or different, one more and why is that when we get sick that we are like immune to most illness such as chiken pox once we get it we don't get it anymore?

2006-12-21 15:54:28 · 4 answers · asked by Leandro 2 in Science & Mathematics Biology

4 answers

T cells are made in the thymus, but ultimately come from hematopoietic stem cells in the bone marrow, from which all blood-cell types begin. A progenitor cell must leave the bone marrow to seed the thymus, eventually giving rise to T cells.

Neutrophils deal with defense against bacterial infection and other very small inflammatory processes and are usually first responders to bacterial infection; their activity and death in large numbers forms pus.

Eosinophils primarily deal with parasitic infections and an increase in them may indicate such.

Basophils are chiefly responsible for allergic and antigen response by releasing the chemical histamine causing inflammation.

Lymphocytes are much more common in the lymphatic system. The blood has three types of lymphocytes:
B cells: B cells make antibodies that bind to pathogens to enable their destruction. (B cells not only make antibodies that bind to pathogens, but after an attack, some B cells will retain the ability to produce an antibody to serve as a 'memory' system.)
T cells: CD4+ (helper) T cells co-ordinate the immune response (they are what becomes defective in an HIV infection) and are important for defence against intracellular bacteria. CD8+ (cytotoxic) T cells are able to kill virus-infected cells. γδ T cells possess an alternative T cell receptor as opposed to CD4+ and CD8+ αβ T cells and share characteristics of helper T cells, cytotoxic T cells and natural killer cells.
Natural killer cells: Natural killer (NK) cells are able to kill cells of the body which are not displaying a signal not to kill them, as they have been infected by a virus or have become cancerous.

Monocytes share the "vacuum cleaner" (phagocytosis) function of neutrophils, but are much longer lived as they have an additional role: they present pieces of pathogens to T cells so that the pathogens may be recognised again and killed, or so that an antibody response may be mounted.

Monocytes are also known as macrophages after they migrate from the bloodstream and enter tissue.

However, to your question about chicken pox, It is called active immunization.

Active immunization is where the actual microbe is taken in by a person. Antibodies are created by the recipient and are stored permanently.

Active immunization can occur naturally when an untreated microbe is received by a person who has not yet come into contact with the microbe and has no pre-made antibodies for defense. The immune system will eventually create antibodies for the microbe, but this is a slow process and, if the microbe is deadly, there may not be enough time for the antibodies to begin being used.

2006-12-21 16:01:58 · answer #1 · answered by Chez 4 · 1 0

T cells are made in the thymus, but ultimately come from hematopoietic stem cells in the bone marrow, from which all blood-cell types begin. A progenitor cell must leave the bone marrow to seed the thymus, eventually giving rise to T cells.

2006-12-21 22:59:15 · answer #2 · answered by mmmm n 2 · 0 1

All T cells ultimately derive from haematopoietic stem cells in the bone marrow. Hematopoietic progenitors derived from haematopoietic stem cells populate the thymus and expand by cell division to generate a large population of immature thymocytes.[1] The earliest thymocytes express neither CD4 nor CD8, and are therefore classed as double negative (CD4-CD8-) cells. As they progress through their development they become double positive thymocytes (CD4+CD8+), and finally mature to single positive (CD4+CD8- or CD4-CD8+) thymocytes that are then released from the thymus to peripheral tissues.

About 98% of thymocytes die during the development processes in the thymus by failing either positive selection or negative selection, while the other 2% survive and leave the thymus to become mature immunocompetent T cells.

2006-12-21 16:02:06 · answer #3 · answered by lipsticklobotomy 2 · 0 1

once you get an illness your body remembers the pattern of it and your antibodies already know how to defeat it.
Thats what a vaccine is, its a small dose of the actual disease or illness enough to get your immune system to built up antibodies against it.
The B cells do the work and the T cells help you can read about it here:

2006-12-21 16:05:39 · answer #4 · answered by Lady Wildwood 3 · 1 0

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