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Chymosin, known also as rennin, is a proteolytic enzyme synthesized by chief cells in the stomach. Its role in digestion is to curdle or coagulate milk in the stomach, a process of considerable importance in the very young animal. If milk were not coagulated, it would rapidly flow through the stomach and miss the opportunity for initial digestion of its proteins.

In order to understand how chymosin coagulates milk, one needs to know something about milk proteins. The majority of milk protein is casein and there are four major types of casein molecules: alpha-s1, alpha-s2, beta and kappa. The alpha and beta caseins are hydrophobic proteins that are readily precipitated by calcium - the normal calcium concentration in milk is far in excess of that required to precipitate these proteins. However, kappa casein is a distinctly different molecule - it is not calcium-precipitable. As the caseins are secreted, they self-associate into aggregates called micelles in which the alpha and beta caseins are kept from precipitating by their interactions with kappa casein. In essence, kappa casein normally keeps the majority of milk protein soluble and prevents it from spontaneously coagulating.

Enter chymosin. Chymosin proteolytically cuts and inactivates kappa casein, converting it into para-kappa-casein and a smaller protein called macropeptide. Para-kappa-casein does not have the ability to stabilize the micellar structure and the calcium-insoluble caseins precipitate, forming a curd.

2006-12-21 01:15:22 · answer #1 · answered by pkababa 4 · 0 2

The enzyme "Renin",that is specially found in bodies of young ages of mammals:
enzyme secreted by the kidney (and also, possibly, by the placenta) that breaks down protein and produces a rise in blood pressure. In the blood, renin acts on a fraction of the plasma proteins and releases angiotensin I. Angiotensin II is formed by the action of converting enzyme, which splits off two amino acids from the 10-amino-acid chain...
HOPE THAT HELPS!!!

2006-12-21 02:55:25 · answer #2 · answered by Andromeda 2 · 1 1

Renin...
Btw, its not rennin.
Rennin is a hormone produce in the kidney to regulate blood pressure.

2006-12-21 01:13:35 · answer #3 · answered by westervel 3 · 1 1

the enzyme is caesin from the inactive carcinogen

2006-12-21 01:40:08 · answer #4 · answered by Paul Quesi 2 · 1 1

uh...gelatin..no wait thats somthing else....im thinking its gotta be Rennin

2006-12-21 01:01:41 · answer #5 · answered by Tiffany 2 · 1 2

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