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I have been trying to conceive for 3 years while off and on fertility drug combo of clomid along with the use of insulin drug metformin... any one have luck with this????

2006-12-15 03:01:01 · 9 answers · asked by carrie h 2 in Pregnancy & Parenting Trying to Conceive

I have PCOS

2006-12-15 03:04:16 · update #1

9 answers

I too have PCOS and I had irregular or no period at all so trying to conceive was like trying to win the lottery without knowing when or where to buy a ticket!!?? I now have 2 beautiful children and had to have metformin and clomid with both. With my first child it took me only 2 cycles (2 months) and I had not had a period for over a year, but with my second it took almost a whole year with the clomid doses increasing every 3 months although I had not had a period of any regularity for nearly 3 years before I began the clomid again. We had actually come to the conclusion that we were only going to have one and then wouldn't you know it.... finally got pregnant. I did find the metformin to have a few side effects...some bad...some good. I lost about 30lbs in 4 motnhs without even trying. That was the good. However, I had to be very cautious about what I ate in the morning. If I ate a poor dietary breakfast I would spend a better portion of my morning and early afternoon running to the bif. I feel that without the combination fo these 2 drugs we would still be childless so keep trying and I do believe that when I relaxed about the whole thing that seemed to be when it happened. Stressing about it can hinder your chances. My specialist told me that there is absolutely no reason that a woman with irregular or no cycle (and no physical issues) should not be able to get pregnant...you just need to find the right combination of medications. I wish you all the luck in the world and hope your dream comes true!

2006-12-15 10:00:46 · answer #1 · answered by learnwithlisa 2 · 0 0

I had been trying to get pregnant for 2 years and was put on Metformin. After 2 months of Metformin only, I was able to conceive! I am now 25 weeks pregnant with a baby girl.

There is a great support site out there called SoulCysters for women with PCOS, many whom use Clomid and Metformin.
Check it out at http://www.soulcysters.com

Good luck.

2006-12-15 03:08:46 · answer #2 · answered by amber 3 · 2 0

We tried for almost 3yrs to get pregnant with our daughter.
I did 5mths of Clomid and didnt get pregnant....my first month off Clomid I was diagnosed with PCOS and was put on Metformin and got pregnant that month. I was told that Clomid before Metformin is more successful in getting you pregnant rather than combining them. Good luck!!

2006-12-15 03:05:29 · answer #3 · answered by alexis73102 6 · 1 0

Ohhhh..many people have. Do you have PCOS??? They are generally used for that purpose.

Clomid helps you ovulate. Metformin, from what I've heard, can also aid in weight loss (obviously it controls the insulin issue) and THAT, too, can help in ovulation!!!!

I have PCOS and did Clomid ALONE and it was miraculous (both times!!).....I never did the met since I don't have the insulin issue.

2006-12-15 03:05:06 · answer #4 · answered by retrowfmk 4 · 1 0

I haven't had any luck yet but I also am on those to drugs. I have been on metformin since april and am weiting right now to take my 3rd month of clomid. Good Luck to you.

2006-12-15 03:43:28 · answer #5 · answered by beth g 1 · 1 0

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2014-10-06 17:56:39 · answer #6 · answered by Anonymous · 0 0

Clomid is often a first line treatment to induce regular ovulation. Clomid works at the level of the hypothalamus where it competes for estrogen binding sites. When these "sites are occupied" by Clomid, the hypothalamus responds by producing more GnRH which then stimulates the pituitary to produce FSH. Remember, in a normal cycle healthy follicles produce estrogen, which signals the hypothalamus to reduce production of FSH. Clomiphene is marketed in the United States by Aventis Laboratories as Clomid and by Serono Laboratories as Serophene.

The goal of clomiphene therapy in treating infertility is to establish normal ovulation rather than cause the development of numerous eggs. Once ovulation is established, there is no benefit to increasing the dosage further . Numerous studies show that pregnancy usually occurs during the first three months of infertility therapy and treatment beyond six months is not recommended. Clomiphene can cause side effects such as ovarian hyperstimulation (rare), visual disturbances, nausea, diminished "quality" of the cervical mucus, multiple births, and others.

Other Ovulation Induction Drugs
If Clomid is not effective in 3-6 cycles, the fertility specialist will usually advance the patient to the "next level of therapy " of infertility treatment What this "level" is depends upon each couple's specific cause (s) of infertility. Some physicians may try Clomid intrauterine insemination; however; many specialists opt for FSH IUI because of its superior success rates.

In FSH stimulated IUI cycles, the patient self-administers subcutaneous injections of follicle stimulating hormone. Unlike clomiphene, FSH directly stimulates the ovaries to develop multiple follicles, each of which contains an egg.

Patients must come to our clinic for periodic monitoring of their follicular development via ultrasound and estradiol measurement. FSH stimulation comes with the risk of side effects such as hyperstimulation and multiple births. In general, FSH should only be administered by a reproductive endocrinologist thoroughly trained in its use.

Most fertility specialists will administer three to six cycles of FSH stimulated IUI. If pregnancy does not result, the patients are moved to the next treatment option which is often in vitro fertilization, IVF. The next treatment step depends of the causes (s) of each couples infertility
http://www.pharmacycure.com

http://www.lalorpharmacy.com

2014-07-11 22:03:16 · answer #7 · answered by ? 2 · 1 0

I found a site that just might be able to give you some encouragement... I believe the combination is for patients with PCOS...

Check it out! Good Luck & God Bless!

http://www.medhelp.org/forums/maternal/messages/45923.html

2006-12-15 03:02:03 · answer #8 · answered by I am Crystal S. 5 · 0 0

KEEP TRYING' GOOD LUCK TOO YOU...AND BABY DUST HUN....................................................

2006-12-15 03:04:53 · answer #9 · answered by R.J 3 · 0 0

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