any interesting facts or ideas about sickle cell disease?

Answer 1

There are several common forms of sickle cell disease. These are called SS (individuals inherit one sickle cell gene from each parent); SC (the child inherits one sickle cell gene and one gene for another abnormal type of hemoglobin called “C”); and S-beta thalassemia (the child inherits one sickle cell gene and one gene for beta thalassemia, another inherited anemia).

In the United States, most cases occur among African-Americans and Hispanic-Americans. About one in every 500 African-Americans has sickle cell disease. It also affects people of Arabian, Greek, Maltese, Italian, Sardinian, Turkish and Indian ancestry.

Answer 2

It is a mutation within the Hemoglobin molecule. There are a few forms of hemoglobin molecules. Babies have variety A, most adults have kind F and so forth. Patients with sickle cellphone have sort S. The trouble with this is that when variety S hemoglobin is disadvantaged of oxygen it motives the purple blood telephone to shange form and become a sickle form. Mostly RBC's are circular and are able to change form to fit through slender capillaries. After they sickle they can no longer alternate form. This causes a sickle cellphone patient to expertise nice ache as blood cells start to again up with strain within the capillaries in the extremities. Customarily it's activated when the sufferer is exercising and turns into short of breath or for every other motive they might be wanting breath. The intriguing factor about sort S hemoglobin is that it is immune to malaria...Which is probably why African humans developed this trait. It helps them fight off malaria, but factors sickle mobile. Once the person has had a sickle mobile challenge the cure is to offer them oxygen to discontinue the cells from sickling. Regrettably, those who have already sickled are lost. Regularly the spleen and liver filter them out leaving the sufferer with fewer RBC's and a slash Hemoglobin which is what anemia is.

Answer 3

Many people with Sickle Cell must have red cell exchanges. They must have their entire blood volume replaced with normal blood cells to relieve their symptoms.

Also, a few patients may have to have bone marrow transplants if their symptoms are severe. I believe that this is done only in children. Plus, it's a fairly new treatment for sickle cell anemia.

Answer 4

You cannot catch Malariaif you already have Sickle Cell. It is prominent in black populations.

Answer 5

people who have or are carriers of sickle cell are immune to malaria, which leads many experts to believe that S.S.A was developed over time to help those people who lived near swampy mosquito ridden areas to fight the malaria.

Answer 6

SSA is the beginning of an evolutionary development of immunity to melanoma caused by exposure to the sun by people who live near the equator.