What is antiphospholipid antibody syndrome?

Question

does anyone have this? How did it affect your pregnancy?

Answer 1

The antiphospholipid syndrome is a disorder of the immune system that is characterized by excessive clotting of blood and/or certain complications of pregnancy (premature miscarriages, unexplained fetal death, or premature birth) and the presence of antiphospholipid antibodies (cardiolipin or lupus anticoagulant antibodies) in the blood. Patients with antiphospholipid syndrome have developed abnormal symptoms while having antiphospholipid antibodies that are detectable with blood testing.

Answer 2

Whoa! I am not a women...so can't answer the pregnancy part but here's what it is friend:

Antiphospholipid syndrome (or antiphospholipid antibody syndrome) is a disorder of coagulation which causes thrombosis in both arteries and veins, as well as recurrent miscarriage. It is due to the autoimmune production of antibodies against cell membrane constituents. It is also referred to as Hughes syndrome after the rheumatologist Dr Graham R.V. Hughes (St. Thomas' Hospital, London, UK) who now works treating Lupus and Hughes Syndrome at the London Lupus Centre.

A very rare form is the catastrophic antiphospholipid syndrome, in which there is rapid organ dysfunction and failure. It carries a high mortality.

Answer 3

Antiphospholipid syndrome (or antiphospholipid antibody syndrome) is a disorder of coagulation which causes thrombosis in both arteries and veins, as well as recurrent miscarriage. It is due to the autoimmune production of antibodies against cell membrane constituents. It is also referred to as Hughes syndrome after the rheumatologist Dr Graham R.V. Hughes (St. Thomas' Hospital, London, UK) who now works treating Lupus and Hughes Syndrome at the London Lupus Centre.

Often, this disease is treated by giving aspirin to inhibit platelet activation, and/or warfarin as an anticoagulant. The goal of the prophylactic treatment is to maintain the patient's INR between 2.0-3.0. It is not usually done in patients who have not had any thrombotic symptoms. During pregnancy, heparin is used instead of warfarin because of warfarin's teratogenicity.

Women with recurrent miscarriage are often advised to take aspirin and to start heparin (or low molecular weight heparin) treatment after missing a period. This is the most effective treatment at the moment.

Answer 4

Anti is against, phoispholipids are fats. So antiphospholipids means can't break down fats. Antibody are those little things that protect us for immunity. Many people have this. Yes, it can effect a pregnancy. Seek MD counsel and advice if you have this.

Answer 5

I don't have it, but I've read a little about it (I looked it up b/c I was curious). It sounds like it might be hard to get pregnant w/ this disorder? One of the signs is repeated miscarriages :(

If you have this disorder, you'll definitely want to talk to your OB about trying to get pregnant, your odds of carrying to term, the risks afterwards (clots can be a BIG problem after birth), and ask if you'll need to see a maternal-fetal medicine doctor (aka perinatologist, a high-risk OB) during your pregnancy.

I wish you all the best!

Answer 6

http://www.medicinenet.com/antiphospholipid_syndrome/article.htm

Answer 7

http://www.medicinenet.com/antiphospholipid_syndrome/article.htm