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i really need help finding this out its driving me crazy!! i've been looking for this answer eery where!!! PLEASE HELP

2006-12-05 05:49:45 · 4 answers · asked by Samantha G 1 in Science & Mathematics Biology

ok ppl are misunderstanding my question... i need to know if the donors antibodies attack the recipients antigens ... i know the recipients antibodies attack the donors antigens i need to know if i can or does go both ways!!!

2006-12-05 08:26:13 · update #1

4 answers

Ok, I totally understand your question. I work in a blood bank. It is possible. For example, if a unit of blood that is donated has a positive antibody screen, it will not be used until all of the plasma has been washed away. Some hospital blood banks would just throw the unit away and not use it.

For the naturally occuring antibodies (anti A and anti B) you would have to get more than one or 2 units to acquire a passive antibody. And this does happen. The patient would just not be able to get their own type of blood until the antibody clears their system. They would have to get O.

Make sense?

2006-12-05 09:05:28 · answer #1 · answered by <3 Chrissy 4 · 0 0

I think that I have this dilemma figured out. For example:
Donor Type O ; No antigens present on surface of red blood cells, Anti A and Anti B antibodies in plasma.

Recipient Type B; Antigen B on surface of RBC; Anti A antibodies in plasma.

It appears that the donor's plasma with Anti B antibodies will react with the recipient's Antigen B on the RBC.

I believe that agglutination doesn't occur because of DILUTION.
Only one pint or so is going into a recipient that has around 12-15 pints of blood. This is a dilution of approx. 1:12; not concentrated enough to cause any harm .

2006-12-05 07:58:10 · answer #2 · answered by ursaitaliano70 7 · 0 0

It does go both ways. Antibodies present in the patients serum can attack the donor red blood cells, and antibodies in the donor serum can attack the patient's red blood cells. The reason you don't worry about the antibodies from the donor is that whole blood is virtually never given to a patient. Instead, the red blood cells are separated from the plasma (which contains the antibodies) and the patient receives just the red cells. This is also why you hear about patients being given a unit of packed red cells instead of a unit of blood.

2016-05-22 21:37:38 · answer #3 · answered by Anonymous · 0 0

The antibodies are filtered out before transfusion.

2006-12-05 06:18:08 · answer #4 · answered by Anonymous · 0 0

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