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Huntingtons disease is caused by a dominant allele.

2006-11-30 14:19:37 · 13 answers · asked by heat92 1 in Science & Mathematics Biology

13 answers

50/50

Woody Guthrie had Huntington's
His son Arlo dodged that genetic timebomb and since Arlo dodged it, so have his kids.

Woody's daughters from a prior marriage were not as lucky as Arlo.

2006-11-30 14:29:18 · answer #1 · answered by WhatAmI? 7 · 0 0

Sorry guys, the inheritence of Huntington's disease does not follow Mendelian laws.
The disease is associated with trinucleotide repeat mutation; the exact risk of getting it from your parents is difficult to assess. Eg.: it is important to know whether your mother or your father had the disease.
So 50% is not an exact answer. Just like in the case of fragile X syndrome, calculate with anticipation!

2006-12-01 04:28:40 · answer #2 · answered by Krumplee 2 · 0 0

25% or 50% depends

The dominant nature of HD increases the chance of the disease occurring in offspring. A heterozygous parent has a 50% chance of a child having the disease as opposed to a homozygous recessive disorder in which even with both parents as carriers, the probability of having child with the disease is only 25%.

2006-11-30 14:21:29 · answer #3 · answered by Medical Teacher 3 · 0 1

1 in 2 or 50%
because one parent has one sick allele & one non sick; you receive 1 allele from each parent so you will get the dominant sick allele from the Huntingtons parent half the time - similar to inheriting a Y chromosome

2006-11-30 14:22:19 · answer #4 · answered by zilmag 7 · 2 0

The danger that you'll inherit the gene is 50%, although the danger that you'll take position the disease is <50%. The penetrance of the disease is amazingly severe, yet certain factors can inform you techniques severe. Successive generations of persons with Hungtington's disease could have better penetrance, besides as paternal vs maternal beginning. the purely authentic thanks to inform is by genetic finding out and counseling.

2016-11-30 00:10:15 · answer #5 · answered by ? 4 · 0 0

Commonly, genetic disorders are autosomal recessive, meaning that they need an affected allele from each parent to inherit the disorder, which is a one in four chance. HD is autosomal dominant, needing only one affected allele from either parent, to inherit the disease, which means there is a one in two chance of inheriting the disorder from an affected parent.

2006-11-30 14:22:58 · answer #6 · answered by DanE 7 · 1 0

It is 50 percent. My husbands step mom has it. She told me the doctor said her children have a one in two chance of getting the disease.

2006-11-30 14:21:42 · answer #7 · answered by unbeatensnailhere 2 · 0 0

For almost all diseases, the risk of possibly getting any of them is 40% or greater if one parent has it, and 80% if both have it.

2006-11-30 14:23:30 · answer #8 · answered by idman31 1 · 0 1

if its caused by a dominant gene then 50%

2006-11-30 14:22:16 · answer #9 · answered by Anonymous · 1 0

If the parent who has the disease has an Rr combination (one dominant, one recessive allele), then:
....R...r
r..Rr..rr
r..Rr..rr
You have a 50% chance of getting the disease.
If the parent with the disease has an RR combo, then:
....R...R
r..Rr..Rr
r..Rr..Rr
You have a 100% chance.

2006-11-30 14:23:11 · answer #10 · answered by thingstealer 2 · 2 1

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