Krebs cycle?

Question

Can someone please explain the steps for me in as much detail as possible?

Answer 1

In the first step of the Krebs Cycle, also known as the CItric Acid Cycle, functions as a metabolic furnace that oxidizes organic fuel derived from pyruvate. The cycle has eight steps, each catalyzed by a specific enzyme. For each turn of the citric acid cycle, two carbons enter in the relatively reduced form of an acetyl group (step 1), and two different carbons leave in the completely oxidized form of carbon dioxide (steps 3 and 4). The acetyl group of acetyl Coenzyme A (CoA) joins the cycle by combining with the compound oxaloacetate, forming citrate (step 1). (Citrate is the ionized form of citric acid, for which the citric acid cycle is named.) The next seven steps decompose the citrate back to oxaloactate. It is this regeneration of oxaloacetate that makes this process a cycle. For each acetyl group that enters the cycle, 3 NAD+ are reduced to NADH (steps 3, 4, and 8). In step 6, electrons are transferred not to NAD+, but to a different electron acceptor, FAD (flavin adenine dinucleotide, derived from riboflavin, a B vitamin). Step 5 in the citric acid cycle forms a GTP molecule directly by substrate-level phosphorylation, when the NADH and FADH2 produced by the citric acid cycle relay the elctrons extracted from food to the electron transport chain. In the process, they supply the necessary energy for the phosphorylation of ADP to ATP. Hope this helps! Crazy answer, I know.

Answer 2

Here you go "Krebs cycle or the citric acid cycle or tricarboxylic acid cycle,occurs in mitochondria, is the common pathway to completely oxidize fuel molecules which mostly is acetyl CoA ,the product from the oxidative decarboxylation of pyruvate.It enters the cycle and passes ten steps of reactions that yield energy and CO2
You can browse the ten steps of reactions through three strands: fact sheet gives the name of enzyme, reaction type,mechanism and prosthetic group; reaction shows the structure of substrate and product(s) and animation presents a short movie clip showing the reaction.
Before going through the TCA cycle, you should know about the oxidative decarboxylation of pyruvate. This reaction links between Glycolysis and TCA cycle."http://www.terravivida.com/vivida/tcasteps/

Answer 3

Good luck with all that!

Answer 4

see this link

http://www.personal.kent.edu/~cearley/PChem/Krebs1.gif