How does Ph effect the chemical reactions of enzymes?

Answer 1

The optimal pH for enzymes is 7 while the temperature is 37 degrees Celsius. When the pH & temperature deviate from this set point, the enzymes (tertiary proteins) will denature (unravel) and lose their active sites and can no longer carry out catalytic processes.

Enzymes are often held in the body in inactive forms so that lower pH of the stomach (HCL) will not destroy its structure. A high pH will slow raise the level of activation energy, thus slowing down the catalytic process.

Answer 2

Each enzyme has an optimal pH range that helps maintain it's normal configuration in an environment which it operates, eg: the optimum pH for amylase is around 7. Some work best in slightly acidic solution(pH<7) and others require alkaline solution(pH>7). A change in pH can alter the normal functioning of the enzyme and in some cases denature it. A denatured protein cannot combine with a substrate.

Answer 3

If temperature is too high, enzymes would denatrue. If temperature is too low, enzyme activity redeuces. Same with PH. A non competitive reaction slows the reaction process because it enables the subtrate to bind to the active site The answer is C

Answer 4

pH will change the charge on the side chains of amino acids present in the enzyme depending on the pKa of the particular R group. Many times the interaction between the enzyme and substrate in the active site is dependent upon the R group being either protonated or unprotonated, and if it is in the improper form due to the pH than this can interfere with the enzyme being able to properly bind the substrate and convert it to product.

Answer 5

pH may cause various amino acids on the polypeptide chain to become protonated and deprotonate. This may cause the overall structure and thus inhibit its function.

Answer 6

Check out this website: http://www.worthington-biochem.com/introBiochem/effectspH.html = lots of good info
Also check out this one: http://www.newton.dep.anl.gov/askasci/bio99/bio99993.htm - a student had your same exact question!
http://www.emc.maricopa.edu/faculty/farabee/BIOBK/BioBookEnzym.html - yet another good one

Hope this helps answer your question!