In terms of occupational health and safety, what is Toxicology?

Answer 1

is the study of the adverse effects of chemicals on living organisms [2]. It is the study of symptoms, mechanisms, treatments and detection of poisoning, especially the poisoning of people. The chief criterion regarding the toxicity of a chemical is the dose, i.e. the amount of exposure to the substance. Almost all substances are toxic under the right conditions

Answer 2

Toxicology is the science of measuring dose and effect relationships between various materials, route of exposure (inhalation, ingestion, contact, etc.), and effects on the organism (in this case, a worker). Toxic implies that the material will have a deleterious effect on the person, resulting in disability or death.

Answer 3

Study of the effects of poisons in living organisms.
HAZMAT requires toxicology findings to make sure employees will be safe around certain chemicals. Or at least are properly guarded from hazardous chemicals.

Answer 4

Toxicology (from the Greek words toxicos and logos is the study of the adverse effects of chemicals on living organisms. It is the study of symptoms, mechanisms, treatments and detection of poisoning, especially the poisoning of people. The chief criterion regarding the toxicity of a chemical is the dose, i.e. the amount of exposure to the substance. Almost all substances are toxic under the right conditions. As Paracelsus, the father of modern toxicology said, “Sola dosis facit venenum” (only dose makes the poison). Paracelsus, who lived in the 16th century, was the first person to explain the dose-response relationship of toxic substances.

Many substances regarded as poisons are toxic only indirectly. An example is "wood alcohol," or methanol, is chemically converted to formaldehyde and formic acid in the liver. It is the formaldehyd and formic acid that cause the toxic effects of methanol exposure. Many drug molecules are made toxic in the liver, a good example being acetaminophen (paracetamol), especially in the presence of alcohol. The genetic variability of certain liver enzymes makes the toxicity of many compounds differ between one individual and the next. Because demands placed on one liver enzyme can induce activity in another, many molecules become toxic only in combination with others. A family of activities that engages many toxicologists includes identifying which liver enzymes convert a molecule into a poison, what are the toxic products of the conversion and under what conditions and in which individuals this conversion takes place.

The term LD50 refers to the dose of a toxic substance that kills 50 percent of a test population (typically rats or other surrogates when the test concerns human toxicity). LD50 estimations in animals became obsolete in 1991 and are no longer required for regulatory submissions as a part of pre-clinical development package.

Mathieu Orfila is considered to be the modern father of toxicology, having given the subject its first formal treatment in 1813 in his Trait des poisons, also called Toxicologie generate.

However, Theostratus Phillipus Auroleus Bombastus von Hohenheim (1493 - 1541) (also referred to as Paracelsus, from his belief that he was above or beyond the work of Celsus - the Roman physician from the first century) is widely regarded as "the father" of modern toxicology. He is credited with the classic toxicology soundbite "All things are poison and nothing is without poison; only the dose makes a thing a poison." The original German reads: "Alle Dinge sind Gift und nichts ist ohne Gift; allein die Dosis machts, dass ein Ding kein Gift ist." This is often condensed to "The dose makes the poison".

Toxi as in toxin, or toxics: dangerous chemicals that dangerously effect our vitals, and ology, or log: the study of something. Like when you log information on a profile. Or logy as in Biology the study of, bio: life. Meaning, it is the study of toxins or dangerous chemicals. What it may be about are, well it's obvious, the toxins we know of, and how they effect a certain variable. One, for example, being humans. In conclusion, toxicology and what it's about, is the study of discovered and existing toxins, and how they work in biological makeup of a physical body, or possibly the ecosystem.

Answer 5

It is the study of toxins.. usually in the body.

As occupational health and safety...this maybe means you should have no drugs or alcohol in your system at work.