Can you help me find the ratio for my following genetics data?

Question

I had to cross and follow the inheritance pattern of Drosophila flies with white eyes. This is a sex-linked recessive trait and is supposed to show up as a 1:1:1:1 ratio. How do I calculate an exact ratio from the data I generated?

F, whi: 103/424
F, red: 118/424
M, whi: 107/424
M, red: 96/424

I understand that it basically supports the 1-1-1-1 ratio, especially through the use of a Chi-square test, but since these values aren't exactly the expected 106-106-106-106 that they're "supposed" to be, what is the exact ratio for my data? Is it still technically 1-1-1-1? How do I go about calculating it?

Thanks!

Answer 1

The exact ratio is:

Fwhi:Fred:Mwhi:Mred = 103:118:107:96 (ratio oif numerators as denominators are all the same)

≈ 0.243 : 0.278 : 0.252 : 0.226 (on expressing fractions as decimals)

≈ 1.07 : 1.23 :1.11 : 1.00 (on dividing all in 1st ratio by 96)

≈ 0.972 : 1.05 : 1.01 : 0.906 (on dividing all in 1st ratio by 106)

Your role would be to use statistics to demonstrate that 1 : 1 : 1 : 1 lies within the bounds of the experiment.

Answer 2

Your ratios are simply 103 : 118 : 107 : 96. If you want to standardize them to the expected value being 106, just divide each number by 106.

So your ratios are 0.9717 : 1.1132 : 1.0094 : 0.9057

Depends on how accurate you want to make them too... to two decimal places: 0.97 : 1.11 : 1.01 : 0.91

Answer 3

The exact ratio is 103:118:107:96 and because these can't be simplified your ratio is just this. You can't manipulate statistics and ratios, you can only simplify.