what is the drug of choice for beta blockers poisioning and why?

Question

pharmacology

Answer 1

1-Current antidotal therapy for ß-blocker poisoning is based on animal studies and case reports. Unfortunately, no prospective human study evaluating optimal therapy has been performed.
2-These therapies include ß-agonists, glucagon, and phosphodiesterase inhibitors. Of these agents, glucagon is generally recognized as first-line therapy because
3-Glucagon is thought to activate adenylate cyclase in cardiac tissue by directly stimulating a G protein on the ß-receptor complex. High-dose glucagon is recommended for cardiotoxicity produced by ß-blocker poisoning.

Answer 2

Beta blockers are relatively very safe drugs, and I don't think there is such a thing as Beta blocker poisoning, Remember, Propanalol has a high I st pass metabolism bust still is given by oral route because it has a very high margin safety and very large doses can also be given.