Hepatitis is a gastroenterological disease, featuring inflammation of the liver. The clinical signs and prognosis, as well as the therapy, depend on the cause.
Signs and symptoms
Hepatitis is characterised by malaise, joint aches, abdominal pain, vomiting 2-3 times per day for the first 5 days, loss of appetite, dark urine, fever, hepatomegaly (enlarged liver) and jaundice (icterus). Some chronic forms of hepatitis show very few of these signs and only present when the longstanding inflammation has led to the replacement of liver cells by connective tissue; the result is cirrhosis. Certain liver function tests can also indicate hepatitis.
Types of hepatitis
Viral
Most cases of acute hepatitis are due to viral infections:
* Hepatitis A
* Hepatitis B
* Hepatitis C
* D-agent (requires presence of the hepatitis B virus)
* Hepatitis E
* Hepatitis F (discredited)
* Hepatitis G
* In addition to the hepatitis viruses, some other viruses can cause hepatitis, including cytomegalovirus, Epstein-Barr virus, yellow fever, etc.
and
Jaundice, also known as icterus (attributive adjective: "icteric"), is a yellowing of the skin, sclera (the white of the eyes) and mucous membranes caused by increased levels of bilirubin in the human body (or the body of another red blooded animal). Usually the concentration of bilirubin in the blood must exceed 2–3 mg/dL for the coloration to be easily visible. Jaundice comes from the French word jaune, meaning yellow.
Causes of jaundice
When red blood cells die, the heme in their hemoglobin is converted to bilirubin in the spleen and in the hepatocytes in the liver. The bilirubin is processed by the liver, enters bile and is eventually excreted through feces.
Consequently, there are three different classes of causes for jaundice. Pre-hepatic or hemolytic causes, where too many red blood cells are broken down, hepatic causes where the processing of bilirubin in the liver does not function correctly, and post-hepatic or extrahepatic causes, where the removal of bile is disturbed.
Pre-hepatic
Pre-hepatic (or hemolytic) jaundice is caused by anything which causes an increased rate of hemolysis (breakdown of red blood cells). In tropical countries, malaria can cause jaundice in this manner. Certain genetic diseases, such as sickle cell anemia and glucose 6-phosphate dehydrogenase deficiency can lead to increase red cell lysis and therefore hemolytic jaundice. Defects in bilirubin metabolism also present as jaundice. Jaundice usually comes with high fevers.
The laboratory findings include:
* Urine: no bilirubin present, urobilirubin > 2 units (except in infants where gut flora has not developed).
* Serum: increased unconjugated bilirubin.
Hepatic
Hepatic causes include acute hepatitis, hepatotoxicity and alcoholic liver disease, whereby cell necrosis reduces the liver's ability to metabolise and excrete bilirubin leading to a build up in the blood. Less common causes include primary biliary cirrhosis, Gilbert's syndrome (a genetic disorder of bilirubin metabolism which can result in mild jaundice, which is found in about 5% of the population) and metastatic carcinoma. Jaundice seen in the newborn, known as neonatal jaudice, is common, occuring in almost every newborn as hepatic machinery for the conjugation and excretion of bilirubin does not fully mature until approximately two weeks of age.
Post-hepatic
Post-hepatic (or obstructive) jaundice, also called cholestasis, is caused by an interruption to the drainage of bile in the biliary system. The most common causes are gallstones in the common bile duct, and pancreatic cancer in the head of the pancreas. Other causes include strictures of the common bile duct, ductal carcinoma, pancreatitis and pancreatic pseudocysts. A rare cause of obstructive jaundice is Mirizzi's syndrome.
The presence of pale stools and dark urine suggests an obstructive or post-hepatic cause as normal feces get their colour from bile pigments. Patients sometimes also complain of itching.
You could get more information from the 2 links below...
2006-10-09 23:31:30
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answer #1
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answered by catzpaw 6
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Hepatitis can be caused by sexual contact or shared needles- and as it progresses, can be fatal. Hepatitis affects the liver, Jaundice occurs in blood diseases, like the liver and gallbladder & causes a yellow discoloring of the eyes, nails, and skin. The hepatitis that I speak of, is type C. ( I think) There are other types- which I do not know much of. Hope this will help some... sorry I couldn't tell you more. Try Google for more help...
2006-10-09 23:12:58
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answer #2
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answered by Anonymous
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Hepatitis causes jaundice by inflaming the liver and causing bile which should flow into the stomach to aid digestion instead to accumulate in the blood. The bile salts cause itching in the hands and feet and cause the skin, nails and eye whites to go yellow. The urine goes brown and faeces goes clay colured due to absence of bile.
Jaundice can also be caused by gallstones blocking the bile duct from the liver to the stomach and causing the same symptoms.
Hepatitis comes, I think, in 5 flavours, Hepatitus A to E. Some are transmitted by sexual contact or shared needles. As hepatitus progresses from A and B to D it can become incurable and fatal. Do a Google search for specifics of the different types.
2006-10-09 23:08:22
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answer #3
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answered by Anonymous
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Hepatitis - Inflammation of the liver. May be caused by bacterial or viral infection, parasitic infestation, alcohol, drugs, toxins, or transfusion of incompatible blood. Although many cases of hepatitis are not a serious health threat, the disease can become chronic and sometimes lead to liver failure and death.literally, inflammation of the liver. Hepatitis caused by a virus is known as viral hepatitis. Other causes of hepatitis include toxic chemicals and alcohol abuse.
Jaundice - a yellowish discoloration of the skin and whites of the eyes due to high bilirubin levels resulting from the breakdown of red blood cells; jaundice is associated with liver damage.
2006-10-09 22:59:08
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answer #4
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answered by Anonymous
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Jaundice is a term that refers to a specific finding on physical examination: yellow eyes. Jaundice is the result of high levels of bilirubin in the blood. There are many causes of jaundice.
If hepatitis is the cause, then additional blood tests are done to exclude viral hepatitis and the other causes of liver disease-
it is only acadamic interest answer given.
2006-10-11 17:42:39
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answer #5
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answered by veerabhadrasarma m 7
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Hepatitis is literally inflammation of the liver and is a disease, while jaundice is the yellowish discoloration of the skin and parts of the eye or even the white frenulum underneath the tongue and is a manifestation of disease.
Old biology textbooks and those not properly updated confuse jaundice as a disease. Jaundice occurs when excess bilirubin is not properly broken down and excreted, thus it occurs in blood diseases, liver and gallbladder diseases, diseases that cause obstruction to bile flow like tumors of the pancreas or strictures (closure or narrowing) of bile canals/channels, and even diseases of the kidneys in later stages.
Hepatitis may be infectious or noninfectious. Infectious hepatitis may be viral, protozoal or bacterial. Rarely, fungal organisms cause hepatitis.
Noninfectious hepatitis include alcoholic hepatitis, toxic hepatitides from other chemicals (like chloroform), biliary hepatitis and those secondary from tumors or new growths.
2006-10-09 23:13:11
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answer #6
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answered by Doctor B 3
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Several viruses are known to cause hepatitis. Common forms of viral hepatitis include Hepatitis A, B, and C:
To know more measures to improve liver you can see all information related to fatty liver diseases at:http://adola.net/go/fattyliver-bible/
2014-07-09 16:47:28
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answer #7
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answered by Anonymous
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hepatitis causes jaundice cos of increased bilirubin in the blood
2006-10-10 08:51:53
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answer #8
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answered by ABHINAV P 2
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both r more or less..d same.
2006-10-11 04:35:22
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answer #9
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answered by pioneer. 2
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