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2006-10-09 12:11:02 · 2 answers · asked by bruce s 1 in Health General Health Care Injuries

2 answers

Amiodarone is an antiarrhythmic medication. Amiodarone affects the way that the heart beats.


Amiodarone (am-ee-OH-da-rone) belongs to the group of medicines known as antiarrhythmics. It is used to correct life-threatening heartbeat problems...

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GENERIC NAME: amiodarone
BRAND NAME: Cordarone
DRUG CLASS AND MECHANISM: Amiodarone is used to correct abnormal rhythms of the heart (an antiarrhythmic medication). Amiodarone was discovered in 1961. Amiodarone was approved by the FDA for clinical use as an antiarrhythmic agent in December of 1985. Although amiodarone has many side effects, some of which are severe and potentially fatal, it has been successful in treating many arrhythmias where other antiarrhythmics fail. Amiodarone is considered a "broad spectrum" antiarrhythmic medication, that is, it has multiple and complex effects on the electrical activity of the heart which is responsible for the heart's rhythm. Among its most important electrical effects are:

a delay in the rate at which the heart's electrical system "recharges" after the heart contracts (repolarization);
a prolongation in the electrical phase during which the heart's muscle cells are electrically stimulated (action potential);
a slowing of the speed of electrical conduction (how fast each individual impulse is conducted through the heart's electrical system);
a reduction in the rapidity of firing of the normal generator of electrical impulses in the heart (the heart's pacemaker);
a slowing of conduction through various specialized electrical pathways (called accessory pathways) which can be responsible for arrhythmias.
In addition to being an antiarrhythmic medication, amiodarone also causes blood vessels to dilate (enlarge). This effect can result in a drop in blood pressure. Because of this effect it also may be of benefit in patients with congestive heart failure.

2006-10-09 12:27:26 · answer #1 · answered by Anonymous · 0 0

Nice explaination

2006-10-10 12:25:36 · answer #2 · answered by usamedic420 5 · 0 0

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