When is a compound both an agonist and an antagonist?

Answer 1

An agonist is a molecule that selectively binds to a specific receptor and triggers a response in the cell. It mimicks the action of an endogenous biochemical molecule (such as hormone or neurotransmitter) that binds to the same receptor. It is a drug molecule (synthesized outside an organism) that reproduces the action of an endogenous natural biochemical (synthesized inside an organism). An agonist is the opposite of an antagonist in the sense that while an antagonist also binds to the receptor, the antagonist does not activate the receptor and actually blocks it from activation by agonists.

In medicine and biology, a receptor antagonist is a ligand that inhibits the function of an agonist and Inverse Agonists for a specific receptor.

Most drugs exert effects, both beneficial and detrimental, by interacting with specific receptors that are present on or within cells. Historically, receptors were thought to act much like light switches. Agonists were thought to turn "on" a single cellular response by binding to the receptor, thus initiating a biochemical mechanism for change within a cell. Antagonists were thought to would turn "off" that response by 'blocking' the receptor from the agonist.

Answer 2

howdy, sounds like you've a good understand-how common. a million. definite, the added drug you provide, the added result you'll see up till all receptors are completely sure to the drug. In pharmacology that is called "Vmax". 2. even with if antagonists block receptors, because those receptors were once occupied and acted upon through agonists, you regularly see the option outcomes of an agonist through giving an antagonist. case in point, beta receptors on the middle p.c. up the middle and develop its power of contraction. in case you provide a beta blocker, the middle will decelerate and settlement a lot less forcefully. wish that helps.