1 week ago diagnosed w ENDOMETRIOSIS n Lupron aka Leuprolide is a treatment to help recovery.Risks?Fertility?

Question

I had emergency laparotomy/laparscopy 9 days ago to discover I had a severe case of endo. My physician is highly recommending Lupron as treatment for 6 months. It is to trick my body in thinking I'm menopausal. If it's successful, It can help my recovery and reduce pain by stopping my periods basically that I know. When I see my doc in a few days to start the treatment, I'm not sure how long after the first treatment series if there'll be a continuance. I'm 19 years old and overall healthy. I wanted a family in 10 years, but now I'm lucky to have 5. Will the treatment affect future HEALTHY pregnancies? How long will I have to be off the treatment b4 I am able to even get pregnant much less a healthy one? Also I only have my right tube left (which was unblocked during surgery b/c of endo took great damage) My left tube ruptured with an ectopic 3 months ago. So my chances now are becoming lower and lower it seems though I've been maintaining hope.Any advice? Info pertaining NEthing

Answer 1

Just done my op last April
Lupron will help if he recommend L it is because you have fibroid inside your tubes and since you wanted chidren it is better to give you shot of lup than removed all of them (you might lost your tube)you can try to get Preg after 45 days of your last shot
but I douth it if you can, I know for a fact that onece you got your period you can try
I had to take it for 3 month i ma not preg yet but my tubes & Uteris are ready & looking wonderful
by the way the treatment of Lup should not effect the future
but help you to have healthy pregnancy
Good Luck

Answer 2

If we were to believe the docs and Takeda Abbott Pharmaceutical's fancy marketing literature and website(s), we'd all think Lupron was the greatest thing since sliced bread. It's not.

It's used for many different uses, both approved and not approved ("off-label"), including Endometriosis, fibroids, alzheimer's (imagine that, since it CAUSES memory loss), central precocious puberty, IVF protocols and prostate cancer, for which it was originally developed and intended for use.

Lupron is a bandaid that does not in any way clear up or cure the condition for which it is being used. Take Endometriosis, for example, which comprises one if its greatest user groups. All it does is temporarily suppress the hormones, thereby - in theory - offering temporary relief of the disease. It does not offer relief in many who use it, and quelling of the hormones is not a cure for Endometriosis. Were that true, removal of the ovaries would be all that was needed and we know that's not the case. Same idea for use in fibroids - it is not in any way curative.

Side effects of Lupron are potentially extremely negative and long-lasting, and include (as reported by the manufacturer itself) Asthenia, General pain, Headache, Hot flashes/sweats, Nausea/vomiting, GI disturbances, Edema, Weight gain/loss, Acne, Hirsutism, Joint disorder, Myalgia, Decreased libido, Depression/emotional lability, Dizziness, Nervousness, Neuromuscular disorders, Paresthesias, Skin reactions at injection site, Breast changes/tenderness/pain, Vaginitis, Flu-like symptoms, Heart palpitations, Syncope, Tachycardia, Appetite changes, Dry mouth, Thirst, Ecchymosis, Lymphadenopathy, Anxiety, Insomnia/Sleep disorders, Delusions, Memory disorder, Personality disorders, Rhinitis, Alopecia, Hair disorder, Nail disorder, Conjunctivitis, Ophthalmologic disorders, Taste perversion, and Dysuria.

And that's just a few. Check the prescribing literature from TAP itself or check a PDR for the long list.

Typically, users of Lupron experience what is known as Clinical Flare, which is an exacerbation of side effects and symptoms during the first 2 injections or so; after about the 3rd injection, the symptoms for which you are using the drug (i.e., Endometriosis) may begin to temporarily decrease.

Hopefully, you will be one of the lucky ones who only experiences minimal side effects for a short time and in whom the drug is effective and has no negative effects.

Barring that, if you're taking it for Endo, look into excision as the definitive treatment for Endo. It's not curative - there is no absolute cure - but excision (see www.centerforendo.com) can confer up 85% long term relief rates. There is a reason the true Endo experts don't use this drug and other GnRHs like it.

GnRH therapy does not confer any beneficial effects towards future fertility, either. Check out...

http://www.endocenter.org/pdf/surgery%20vs.%20gnrh.pdf
Surgery versus the Use of Lupron Depot as Treatment

http://www.endocenter.org/pdf/PreDiagnosisGnRH.pdf
Use of Lupron Depot Prior to Surgical Diagnosis

http://groups.yahoo.com/group/erc
Free discussion and support group for Endo

And let us not forget that TAP and many of Lupron's prescribing physicians were prosecuted under the federal RICO violations act in the largest pharmaceutical lawsuit in history - over $875 million in fines were paid out - due to their unethical pricing and fraud schemes in conjunction with prescribing Lupron to patients in exchange for kickbacks from the company.

Good luck to you.

Answer 3

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Answer 4

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Answer 5

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