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staphylococcal bone and joint infections, peritonitis; endocarditis prophylaxis [unlicensed indication],
Cautions discontinue immediately if diarrhoea or colitis develops; hepatic impairment (Appendix 2); renal impairment; monitor liver and renal function on prolonged therapy and in neonates and infants; pregnancy (Appendix 4); breast-feeding (Appendix 5); avoid rapid intravenous administration; avoid in porphyria (section 9.8.2); interactions: Appendix 1 (clindamycin)

Contra-indications diarrhoeal states; avoid injections containing benzyl alcohol in neonates (see under preparations below)

Side-effects diarrhoea (discontinue treatment), abdominal discomfort, oesophagitis, nausea, vomiting, antibiotic-associated colitis; jaundice; leucopenia, eosinophilia, and thrombocytopenia reported; rash, pruritus, urticaria, anaphylactoid reactions, Stevens-Johnson syndrome, exfoliative and vesiculobullous dermatitis reported; pain, induration, and abscess after intramuscular injection; thrombophlebitis after intravenous injection

Dose
By mouth, 150–300 mg every 6 hours; up to 450 mg every 6 hours in severe infections; child, 3–6 mg/kg every 6 hours

Counselling Patients should discontinue immediately and contact doctor if diarrhoea develops; capsules should be swallowed with a glass of water.

By deep intramuscular injection or by intravenous infusion, 0.6–2.7 g daily (in 2–4 divided doses); life-threatening infection, up to 4.8 g daily; single doses above 600 mg by intravenous infusion only; single doses by intravenous infusion not to exceed 1.2 g; child over 1 month, 15–40 mg/kg daily in 3–4 divided doses; severe infections, at least 300 mg daily regardless of weight


Clindamycin has only a limited use because of serious side-effects. Its most serious toxic effect is antibiotic-associated colitis which may be fatal and is most common in middle-aged and elderly women, especially following operation. Although antibiotic-associated colitis can occur with most antibacterials it occurs more frequently with clindamycin. Patients should therefore discontinue treatment immediately if diarrhoea develops.

Clindamycin is active against Gram-positive cocci, including penicillin-resistant staphylococci and also against many anaerobes, especially Bacteroides fragilis. It is well concentrated in bone and excreted in bile and urine.

Clindamycin is recommended for staphylococcal joint and bone infections such as osteomyelitis, and intra-abdominal sepsis.

Clindamycin is used for prophylaxis of endocarditis in patients allergic to penicillin [unlicensed indication],

Oral infections
Clindamycin should not be used routinely for the treatment of oral infections because it may be no more effective than penicillins against anaerobes and there may be cross-resistance with erythromycin-resistant bacteria. Clindamycin can be used for the treatment of dentoalveolar abscess that has not responded to penicillin or to metronidazole.

2006-09-21 02:58:03 · answer #1 · answered by heleneaustin 4 · 0 0

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2016-12-24 20:28:15 · answer #2 · answered by Anonymous · 0 0

Yes, titanic really happened. Titanic was a boat deemed unsinkable by the general populace. It hit an iceberg and sank. A lot of people died and many lived. The movie was many years later then the actual sinking. Think of it like the vietnam wars that come out now. Were they filming at the vietnam war to make an hour and a half movie filled with romantic drama and brotherly love? Nope!! Besides Leonardo DiCarprio wasn't even alive when the Titanic was built and sank!! Also, the type of cameras needed to capture color and video were not invented when the titanic sank...

2016-03-17 23:34:41 · answer #3 · answered by ? 4 · 0 0

This is a very strong antibiotic and it is used in medical practice only to treat severe bacterial infections that cannot be treated by any other antibiotic. It can be used to treat skin, lung, pelvic and vaginal infections. As a topical ointment or a gel it is used in 1 % concentration. It is very effective against heavy forms of acne, it treats the bacterial infections on the skin and it eases the symptoms of acne. The main ingredient of the gel is alcohol and that’s why gel itself is very flammable, you shouldn’t be using the gel near an open flame or if youre smoking. When taking clyndamycin orally many side effects may appear, one of the worst ones is pseudomembranous colitis, and other stomach and digestive tract problems.

2006-09-21 02:50:32 · answer #4 · answered by cyber chick 2 · 1 0

That's 150 mg, not grams.

"Clindamycin, an antibiotic, is used to treat infections of the respiratory tract, skin, pelvis, vagina, and abdomen. Antibiotics will not work for colds, flu, or other viral infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information."
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682399.html

"Clindamycin is used orally in dosages of 150 to 450 mg q 6 h in adults and 10 to 30 mg/kg/day in 3 to 4 divided doses in children. The IM or IV dosage is 600 to 2700 mg/day in 3 to 4 equal doses in adults and 20 to 40 mg/kg/day in 3 or 4 equal doses in children.
http://www.merck.com/mrkshared/mmanual/section13/chapter153/153d.jsp

2006-09-21 02:47:31 · answer #5 · answered by Jim 5 · 1 0

Definition 1:
clindamycin
An antibiotic that may be an alternative treatment for PCP and toxoplasmosis. The most common side effect is diarrhoea.

Overgrowth of an intestinal bacterium called Clostridium difficile is responsible for the diarrhoea during clindamycin therapy.

(12 Jan 1998)

Definition 2:
clindamycin (clin·da·my·cin) (klin”də-mi´sin) a semisynthetic analogue of the natural antibiotic lincomycin from which it is produced by chlorination; it is effective primarily against gram-positive bacteria.

c. hydrochloride [USP] the hydrated hydrochloride salt of clindamycin; used primarily in the treatment of penicillin-resistant gram-positive infections and in patients allergic to penicillin; administered orally.

c. palmitate hydrochloride [USP] a water-soluble hydrochloride salt of the ester of clindamycin and palmitic acid, having the same actions and uses as the hydrochloride salt; it is suitable for the preparation of solutions for oral administration.

c. phosphate [USP] a water-soluble ester of clindamycin and phosphoric acid, having the same actions and uses as the hydrochloride salt; administered intramuscularly or intravenously. It is also used topically in the treatment of acne vulgaris and vaginally in the treatment of bacterial vaginosis.

2006-09-21 02:58:56 · answer #6 · answered by anieska 3 · 1 0

sounds like an antibiotic.

But 150g is a HUGE dose.

I think you mean 150mg.

2006-09-21 02:46:42 · answer #7 · answered by Anonymous · 0 0

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2017-03-01 04:07:44 · answer #8 · answered by ? 3 · 0 0

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2017-03-01 04:02:13 · answer #9 · answered by ? 3 · 0 0

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2017-02-27 23:26:01 · answer #10 · answered by ? 3 · 0 0

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