What is the chemical name for ROHYPNOL? What are the merits and demerits of it? For what purpose it is used?

Answer 1

Flunitrazepam (formerly marketed under the trade name Rohypnol in North America, pronounced ˌfluːnaɪˈtræzəpæm) is a drug which is a benzodiazepine derivative. It has powerful sedative, anxiolytic, and skeletal muscle relaxant properties.

History

Flunitrazepam was first synthesized in the early 1970s by Roche and was used in hospitals when deep sedation was needed. It first entered the commercial market in Europe in 1975, and in the 1980s it began to be available in other countries.

It originally came in 1 mg, 2 mg, and 5 mg sizes, but due to its potency and potential for abuse, the higher doses were taken off the market and it is now only available in 1 mg.

Medical uses

Flunitrazepam has not been approved by the Food and Drug Administration for medical use in the United States. It is available only by private prescription in the United Kingdom[1] (though Rohypnol was discontinued in 1986, Rophynol use is still present in modern culture) and prescription in Australia is restricted.[2][3] It is used primarily for the treatment of severe insomnia that has not responded to other treatments.

Abuse Potential

Drug-facilitated Sexual Assault

Flunitrazepam is known to induce anterograde amnesia in sufficient doses; individuals are unable to remember certain events that they experienced while under the influence of the drug. This effect is particularly dangerous when flunitrazepam is used to aid in the commission of sexual assault; victims may not be able to clearly recall the assault, the assailant, or the events surrounding the assault.

It is difficult to estimate just how many flunitrazepam-facilitated rapes have occurred in the past. Very often, biological samples are taken from the victim at a time when the effects of the drug have already passed and only residual amounts remain in the body fluids. These residual amounts are difficult, and sometimes impossible, to detect using standard screening assays available in the United States. If flunitrazepam exposure is to be detected at all, urine samples need to be collected within 72 hours and subjected to sensitive analytical tests. The problem is compounded by the onset of amnesia after ingestion of the drug, which causes the victim to be uncertain about the facts surrounding the rape. This uncertainty may lead to critical delays or even reluctance to report the rape and provide appropriate biological samples for testing. If a person suspects that he or she is the victim of a flunitrazepam-facilitated rape, he or she should get laboratory testing for flunitrazepam as soon as possible.

It must be noted that an inability to remember events, including sexual encounters, is not conclusive evidence of having consumed a drugged drink: Drunkenness itself causes blackouts, sleepiness, and a reduction in inhibitions. Only a timely screening for flunitrazepam can demonstrate its use.

Answer 2

Rohypnol (flunitrazepam)

Rohypnol (flunitrazepam), most commonly known as a date-rape drug, continues to be abused among teenagers and young adults, usually at raves and nightclubs. The drug remains readily available, mainly through pharmaceutical operators located in Mexico, especially Tijuana.
Rohypnol is marketed by Hoffman-La Roche Inc., and is legally sold in Latin America and Europe as a short-term treatment for insomnia, and as a preanesthetic medication. One of the significant effects of the drug is anterograde amnesia, a factor that strongly contributed to its inclusion in the Drug-Induced Rape Prevention and Punishment Act of 1996. Anterograde amnesia is a condition in which events that occurred while under the influence of the drug are forgotten.

Rohypnol is available as a .5-milligram and 1-milligram oblong tablet, as well as a 1-milligram per milliliter injectable solution. Hoffman-La Roche phased out the 2-milligram dose tablet from 1996 to 1997, and is currently phasing out the round, white 1-milligram tablet. The licit market for the drug is currently supplied with a 1-milligram dose in an olive green, oblong tablet, imprinted with the number 542. The new tablet includes a dye that, according to Hoffman-La Roche, will be visible if it is slipped into a drink. Reports indicate that Rohypnol is often sold for between $2 and $5 per dosage unit, although it may sell for from $10 to $30 per dosage unit.

Answer 3

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Answer 4

Rohypnol Formula

Answer 5

Rohypnol, clinically known as flunitrazepam and perhaps more well-known as Roofies, has the chemical formula, C16H12FN3O3 and chemical name, 5-(2-fluorophenyl)-1,3-dihydro-1-methyl-7-nitro-2H-1,4-benzodiazepin-2-one. Rohypnol belongs to the family of medications called benzodiazepines which includes Valium (diazepam), Librium (chlorodiazepoxide) and Xanax (alprazolam). Benzodiazepines (BDZ) are a class of anxiolytic, anticonvulsant, and sedative-hypnotic drugs, designed to reduce anxiety and nervousness, prevent convulsions, and produce a relaxed state. A good example would be sleeping pills, and as flunitrazepam is ten times more powerful than Valium, it is often used as a short-term treatment for insomnia.

Answer 6

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Answer 7

Plz visit this link

http://en.wikipedia.org/wiki/Rohypnol

Answer 8

DUH ! Watch the news or read a paper. It's a date rape drug ! Anyone who tells you how to make it should be reported for contributing after the fact !

Answer 9

Flunitrazepam

Flunitrazepam (formerly marketed under the trade name Rohypnol in North America, pronounced ˌfluːnaɪˈtræzəpæm) is a drug which is a benzodiazepine derivative. It has powerful sedative, anxiolytic, and skeletal muscle relaxant properties.

Pharmacology
Like other benzodiazepines, flunitrazepam's pharmacological effects include sedation, muscle relaxation, reduction in anxiety, and prevention of convulsions. However, flunitrazepam's sedative effects are approximately 7 to 10 times more potent than diazepam. The effects of flunitrazepam appear approximately 15 to 20 minutes after oral administration, and last for approximately four to six hours. Some residual effects can persist up to 12 hours or more after administration.

[edit]
Medical uses
Flunitrazepam has not been approved by the Food and Drug Administration for medical use in the United States. It is available only by private prescription in the United Kingdom[1] (though Rohypnol was discontinued in 1986, Rophynol use is still present in modern culture)

In the UK it is also used in some hospitals to sedate patients undergoing colonoscopy.

Prescription in Australia is restricted.[2][3] It is used primarily for the treatment of severe insomnia that has not responded to other treatments.

Abuse Potential
[edit]
Drug-facilitated Sexual Assault
Flunitrazepam is known to induce anterograde amnesia in sufficient doses; individuals are unable to remember certain events that they experienced while under the influence of the drug. This effect is particularly dangerous when flunitrazepam is used to aid in the commission of sexual assault; victims may not be able to clearly recall the assault, the assailant, or the events surrounding the assault.

It is difficult to estimate just how many flunitrazepam-facilitated rapes have occurred in the past. Very often, biological samples are taken from the victim at a time when the effects of the drug have already passed and only residual amounts remain in the body fluids. These residual amounts are difficult, and sometimes impossible, to detect using standard screening assays available in the United States. If flunitrazepam exposure is to be detected at all, urine samples need to be collected within 72 hours and subjected to sensitive analytical tests. The problem is compounded by the onset of amnesia after ingestion of the drug, which causes the victim to be uncertain about the facts surrounding the rape. This uncertainty may lead to critical delays or even reluctance to report the rape and provide appropriate biological samples for testing. If a person suspects that he or she is the victim of a flunitrazepam-facilitated rape, he or she should get laboratory testing for flunitrazepam as soon as possible.

It must be noted that an inability to remember events, including sexual encounters, is not conclusive evidence of having consumed a drugged drink: Drunkenness itself causes blackouts, sleepiness, and a reduction in inhibitions. Only a timely screening for flunitrazepam can demonstrate its use.

[edit]
Drug-facilitated Robbery
In the United Kingdom, the use of flunitrazepam and other "date rape" drugs has been connected to stealing from sedated victims. One expert quoted in a British tabloid estimated that up to 2,000 individuals are robbed each year after being spiked with powerful sedatives [1], making drug-assisted robbery a more common problem than drug-assisted rape.

Criminals sometimes use flunitrazepam before committing robbery as it has a calming and anti-emotive effect. This allows the criminal to perform the robbery without becoming anxious. Flunitrazepam is also known to induce anterograde amnesia making police interrogations more difficult.[4][5][6]

In a notable flunitrazepam related case, Selina Hakki was found guilty in December 2004 of using flunitrazepam to drug wealthy men and rob them of their clothes and accessories in the UK.

Recreational drug
Although flunitrazepam has become widely known in USA for its use as a date-rape drug, it is used more frequently as a recreational drug. It is used by high school and college students, rave party attendees, and heroin and cocaine users (who call a dose of flunitrazepam a "roofie") for recreational purposes, including:

To produce profound intoxication (Kurt Cobain overdosed on a mixture of flunitrazepam and champagne several weeks before his death)
To boost the high produced by heroin, or ease the anxiety and/or sleeplessness of withdrawal
To counteract the side effects of stimulants (e.g. insomnia, paranoia, jitteriness)
To "soften" the so-called "crash" which follows heavy usage of stimulants, such as cocaine or methamphetamine
To improve sex drive and appetite.
Flunitrazepam is usually consumed orally, and is often combined with alcohol. It is also occasionally insufflated (i.e. tablets are crushed into powder and snorted). In some European countries, there was an alcohol solution of flunitrazepam (Darkene), abused by injection, with very strong effects.

Side effects
Flunitrazepam is considered to be one of the most addictive of the benzodiazepines, along with clonazepam, midazolam, temazepam, lorazepam and alprazolam. Its use causes several notable side effects, including:

Drowsiness
Loss of motor control
Dizziness
Lack of coordination
Slurred speech
Confusion
Gastrointestinal disturbances, lasting 12 or more hours.
Respiratory depression in higher doses
Long-term use of flunitrazepam can result in psychological and physical dependence and the appearance of withdrawal symptoms when the drug is discontinued. Flunitrazepam impairs cognitive and psychomotor functions, affecting reaction time and driving skill. The use of this drug in combination with alcohol potentiates these side effects, and can lead to toxicity.

Legal status
Flunitrazepam is currently a Schedule III drug under the international Convention on Psychotropic Substances of 1971 [2]; in the United States it was initially placed into Schedule IV with other benzodiazepines, under the Controlled Substances Act of 1984, and was later moved to Schedule III.

According to FDA Associate Director for Domestic and International Drug Control Nicholas Reuter[3]:

Flunitrazepam was "temporarily controlled in Schedule IV pursuant to a treaty obligation under the 1971 Convention on Psychotropic Substances. At the time flunitrazepam was placed temporarily in Schedule IV . . . there was no evidence of abuse or trafficking of the drug in the United States."
Rophynol is currently under consideration to be rescheduled to Schedule I, and is already considered such in the States of Florida, Idaho, Minnesota, New Hampshire, New Mexico, North Dakota, Oklahoma, and Pennsylvania.

21 U.S.C. § 841 and 21 U.S.C. § 952 provide for stiff prison terms for the possession of flunitrazepam; penalties for use or distribution include life in prison, should death or serious injury occur.

In Australia, flunitrazepam is a schedule 8 drug, along with amphetamines and narcotic analgesics. All other benzodiazepines are schedule 4 drugs. Unauthorised possession of certain quantities of the drug is punishable by criminal sanctions in New South Wales under Schedule 1 of the Drug Misuse and Trafficking Act 1985.

Street Terms
Street Terms for Rohypnol:

Circles
Forget me drug
Forget me pill
Getting roached
La Rocha
Lunch money drug
Mexican valium
Pingus
R-2
Reynolds
Rib
Roach-2
Roapies
Robutal
Roofies
Rope
Rophies
Row-shay
Ruffles
Wolfies