What does the term MAIO inhibiting drugs mean?

Question

I was asked about drug interactions and this term came up. My question is what drugs are considered maio inhibitors.

Answer 1

I think you mean MAOI??

Monoamine Oxidase Inhibitors (MAOI)
drugs and trade names:
• Furazolidone: Furoxone
• Isocarboxazid: Marplan®
• Isoniazid: Laniazid®, Nydrazid®
• Isoniazid rifampin: Rifamate®, Rimactane®/INH
• Moclobemide
• Pargyline: Eutonyl®
• Phenelzine: Nardil®
• Procarbazine: Matulane®
• Selegiline: Atapryl®, Deprenyl®, Eldepryl®
• Tranylcypromine: Parnate®

type of drug:
Two groups:
• Hydrazine derivatives: phenelzine, isocarboxazid
• Non-hydrazine derivatives: tranylcypromine, pargyline

mechanism: Agents that inhibit monoamine oxidase and alter catecholamine metabolism (down-regulating noradrenergic synpases and upregulating serotogenic synapses); includes other agents with secondary MAOI action, e.g., phenelzine.

used to treat: Depression (refractory to tricyclic antidepressants); antineoplastic (procarbazine), antibiotic (furoxone); adjunctive treatment in Parkinson's (selegine) and hypertension (pargyline).

Answer 2

Mono Amine Oxidase Inhibitors - MAOI

See the wiki page about it

They are old fashioned antidepressants and associated with the necessity to stick to a particular diet and avoid certain foods.

There is a new class of MAOI's now, the RIMA's Reversible Inhibitors of Monoamine oxidase A: moclobemide

This is a better drug as it is safer and does not require the diet. It is considered a mild antidepressant as it's efficacy is not quite up to par with the hard core tricyclics and SSRI's

The wiki page has a list of the names of these:
# Isocarboxazid (Marplan)
# Moclobemide (Aurorix, Manerix, Moclodura®)
# Phenelzine (Nardil)
# Tranylcypromine (Parnate)
# Selegiline (Selegiline, Eldepryl), and Emsam
# Nialamide
# Iproniazid (Marsilid, Iprozid, Ipronid, Rivivol, Propilniazida)
# Iproclozide
# Toloxatone

Answer 3

I asked my doctor recently. It is a group of drugs that used to be used for treating depression. They are still used but not very often. I don't have the names of the drugs but if you aren't being treated for depression, you should be ok. If in doubt, call a 24 hr. pharmacy and ask to speak to the pharmacist.

Answer 4

Certain types of antideppressants. (BTW, it's MAOI) Look this up on the internet and it will give you the names of them. Most health care professionals are steering away from these now because of the many interactions with other meds and even foods, such as cheese and wine.

Answer 5

Maoi Drug Names

Answer 6

it means it looks like a drug but its not the same drug

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