I want to take the Progesterone only pill but am worried about side effects. Has it any benefits ?

Question

I can't take the combined pill as I gain weight rapidly, feel sick and over eat whilst taking it ! Does the POP have any benefits ?

I am mainly concerned about weight gain, mood swings and reduced sex drive. I already know how it works ! I am specifically concerned with side effects. can it help PMS or could it make it worse ? I am over 40 and already have two kids.

Answer 1

take and if it don't suit you change it there is no way of knowing how your body is going to react to the pill

Answer 2

I had to quit the combined pill because I get migraines, and the POP was the best thing ever for me!

I had virtually no sex drive on the combined pill but it was back and better than ever on the POP.

After a few months though, the one I was taking (Micronor) wasn't as effective and I was constantly bleeding. My GP said this was because it wasn't strong enough for me (eep!).

I don't think I gained any weight on it, in fact I lost about half a stone after coming off the combined pill and switching.

I'm not taking any contraception now, as my partner and I would quite like to get pregnant (although we're not actively trying yet, just hoping for an "oops!"), but if I need to take contracteption again I would definately take the POP. However, my only issue was I am quite scatterbrained and often couldn't remember to take it, so I might try Implanon (PO Implant) next time.

Answer 3

Hi i had to come of the combined pill as it did the same to me, and the nurse recommended me Cerazette and it is brilliant its a progestrone only pill like the POP but it have a 12 hour window where you can take it if you have missed it rather than a 3 hour window like the POP. I find it is brilliant, i havent put on any weight as i dont get the urge to over eat like i did on the combined pill and i never feel sick in the morning now either. The only thing is you have to take it continously so you dont have a brake, but you also dont have a period either and no cramps or anything, so i love it. But it depends on if you like having a brake or you dont mind. Some people do bleed more, but this didnt happen with me.
I know how you feel when one pill has made you gain weight you are scared another will, everytime i started a new pack of the combined pill i nearly put on half a stone. But with the POP/Cerazette as it only contains Progestrone then it shouldnt have the effects, the only thing i found it made me have a few more spots than usuall but id rather have spots that you can treat than put my health at risk being overweight. Just have a word with one of the nurses and she will point you in the right direction.

Answer 4

I tried Micronor, but it ended up making me feel horrible. I had breakthrough bleeding constantly. Turned out that the low dose (progesterone only) pill was not a good fit for me. I had a problem with having too little estrogen. But everyone woman is different. You could try it, and if it doesn't work out try something else. There are so many different types out there now.

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Answer 7

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Answer 8

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Answer 9

Progesterone Only Pills or Progestin Only Pills (POP) are contraceptive pills that only contain progestins (synthetic hormones similar to progesterone) and do not contain estrogen. They are colloquially known as mini pills.

Although such pills are often called "Progesterone Only Pills," they do not actually contain progesterone, but one of several chemically related compounds and there are a number of progesterone only contraceptive formulations.



--How they work--
The mechanism of action of progestogen-only contraceptives depends on the progestogen activity and dose.

Very low dose progestogen-only contraceptives, such as traditional progestogen-only pills (and subdermal implants Norplant and Jadelle and intrauterine systems Progestasert and Mirena), inconsistently inhibit ovulation in ~50% of cycles and rely mainly on their progestogenic effect of thickening the cervical mucus and thereby reducing sperm viability and penetration.

Intermediate dose progestogen-only contraceptives, such as the progestogen-only pill Cerazette (or the subdermal implant Implanon), allow some follicular development but much more consistently inhibit ovulation in 97–99% of cycles. The same cervical mucus changes occur as with very low dose progestogens.

High dose progestogen-only contraceptives, such as the injectables Depo-Provera and Noristerat, completely inhibit follicular development and ovulation. The same cervical mucus changes occur as with very low dose and intermediate dose progestogens.

In anovulatory cycles using progestogen-only contraceptives, the endometrium is thin and atrophic. If the endometrium was also thin and atrophic during an ovulatory cycle, this could theoretically interfere with implantation of a blastocyst (embryo).


--Efficacy--
The theoretical efficacy is similar to that of Combined Oral Contraceptive Pill (COCP). However, they are taken continuously without any breaks between packets and traditional progestogen-only pills must be taken to a much stricter time every day (within 3 hours vs. a COCP's 12 hours, although in some countries the POP Cerazette has an approved window of 12 hours). The real-life efficacy is therefore dependent upon user compliance.

POPs are not dependent upon gut bacterial flora for their absorption and so are not affected by courses of antibiotics. They will, however, be affected by any episodes of diarrhoea or vomiting.


--Benefits--
Lacking the oestrogen of combined pills, they are not associated with increased risks of DVT or heart disease. With the decreased clotting risk, they are not contraindicated in the setting of sickle-cell disease. The low dose of progesterone, and absence of estrogen, make the minipill safe to use during breastfeeding; in fact, it may increase the flow of milk. Like combined pills, the minipill decreases the likelihood of pelvic inflammatory disease.

It is unclear whether POPs provide protection against endometrial cancer and ovarian cancer to the extent that COCP do.


--Side effects--
With no break in the dosage, bleeds do not initially occur at a predictable time. Most women tend to establish, over a few months, light spotting at approximately regular intervals.
May cause mastalgia or mood swings.
Weight gain is less commonly experienced than on COCP.

--Breast cancer risk--
Epidemiological evidence on POPs and breast cancer risk is based on much smaller populations of users and so is less conclusive than that for COCPs.

In the largest (1996) reanalysis of previous studies of hormonal contraceptives and breast cancer risk, less than 1% were POP users. Current or recent POP users had a slightly increased relative risk (RR 1.17) of breast cancer diagnosis that just missed being statistically significant. The relative risk was similar to that found for current or recent COCP users (RR 1.16), and as with COCPs, the increased relative risk decreased over time after stopping, vanished after 10 years, and was consistent with being due to earlier diagnosis or promoting the growth of a preexisting cancer.[2][3]

The most recent (1999) IARC evaluation of progestogen-only hormonal contraceptives reviewed the 1996 reanalysis as well as 4 case-control studies of POP users included in the reanalysis. They concluded that: "Overall, there was no evidence of an increased risk of breast cancer" with progestogen-only contraceptives, but since there was "inadequate evidence", they were "possibly carcinogenic".[4]

Recent anxieties about the contribution of progestogens to the increased risk of breast cancer associated with HRT in postmenopausal women such as found in the WHI trials[5] have not yet spread to progestogen-only contraceptive use in premenopausal women.[1]