Which is stonger: the 3',5' phosphodiester bond between the phosphate group and the deoxy ribose sugar, OR the Beta glycosidic linkage between the deoxyribose sugar and the nitrogenous base?? How can i callculate the energy needed to break the bond in both cases? please help...
2006-09-12 01:37:19 · 4 answers · asked by malaysia 2 in Science & Mathematics ➔ Biology
It is quite complicated. Unfortuantely I don't have access to the following journal, but if you have, you should have a look.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16483232&dopt=Abstract
2006-09-12 02:54:16 · answer #1 · answered by bellerophon 6 · 0⤊ 0⤋
The phosphodiester bond consists of a -P--O--C- bond, whereas the glycosidic bond is a -C--O--N- bond.
The values for each of the bonds involved in kJ/mol are as below:
P--O: 335
C--O: 358
N--O: 201
Hence by just the bond energies above, the bond energy of the phosphodiester bond and the glycosidic bond can be derived by addtion.
By the above definition of the bonds (you may define them otherwise, it depends on your syllabus), the phosphodiester bond is stronger with 693 kJ/mol of energy required to break it compared to that of the glycosidic bond which only requires 595 kJ/mol to break it.
A comprehensive list of the bond energy values is found at the source provided below. Hope this helped! :)
2006-09-12 02:11:34 · answer #2 · answered by musicalif3 2 · 0⤊ 0⤋
HAHAHA at first I read that as ''what is the strongest human bone?'' And I open the question thinking ''The skull'' and I'm scrolling down to write that, and I notice the answers and I'm like what the hell? Am I missing something? Rofl, anyway my answer is NOT the skull...strongest human BOND (=P) is love.
2016-03-26 21:41:36 · answer #3 · answered by ? 4 · 0⤊ 0⤋
phosphodiester bond
2006-09-12 01:47:59 · answer #4 · answered by yacheckoo 4 · 0⤊ 0⤋