Genes and Protiens?

Question

Does Anyone Have a Clear Definition of a Gene? Does it Include Regurlatory Sequences?

I'm Inclined to Think a Gene Only has Structural Sequences, Not Regulatory Ones, but I Can Be Wrong.

Answer 1

"Region of DNA that controls a discrete hereditary characteristic, usually corresponding to a single protein or RNA. This definition includes the entire functional unit, encompassing coding DNA sequences, noncoding regulatory DNA sequences and introns"

from "Molecular biology of the cell" by Alberts et al, 3rd edition.

In practice however I have seen the term "gene" used most of the time only for the coding DNA sequence at least when recombinant DNA is involved. So if you are talking about a human gene in the human chromosome you are talking about the whole functional unit, but if you have cloned the coding DNA sequence of lacZ in a plasmid you can also say that you have the lacZ gene expressed by e.g. the lac promoter.

Answer 2

Gene was originally defined through genetics experiments (big surprise) showing different forms of the gene (alleles) causing different physical forms of the organism (phenotype). Over time many different alleles were found to exist for a given gene - sometimes with subtle differences. When molecular biology arrived on the scene the corresponding DNA sequences were found to be both structural sequences (coding regions) and nonstructural sequences (introns and regulatory regions). So, the gene encompasses both regulatory and structural components that contribute to the function of the gene.

Answer 3

Genes are the units of heredity in living organisms.
A Regulatory Sequence is part of a gene with a specific function, turn on and off parts of the gene.
A regulatory sequence (also called regulatory region or ~ element) is a promoter, enhancer or other segment of DNA where regulatory proteins such as transcription factors bind preferentially. They control gene expression and thus protein expression.

Answer 4

Definition of Gene

Many molecular definitions of a gene relate to their role in directing the production of specific proteins. This stems from the analysis of mutants where it was shown that the absence of a specific protein was related to the mutation. Proteins are key components in the central dogma as polymerases but they also have other key metabolic roles. These roles are:

Enzymatic
Structural components
Regulatory roles

Answer 5

Gen is a port of DNA molecule that shows some objectives of a person. like the colour of the hair or eyes and...