what is resveratrol?do you have medical literature for resveratrol?

Question

would you show me some medical literature for resveratrol?

Answer 1

Resveratrol

TRADE NAMES
Protykin Resveratrol (Natrol), Resveratrol Antioxidant Protection (Source Naturals).

DESCRIPTION
Resveratrol is a naturally occurring phytoalexin produced by some higher plants in response to injury or fungal infection. Phytoalexins are chemical substances produced by plants as a defense against infection by pathogenic microorganisms, such as fungi. Alexin is from the Greek, meaning to ward off or to protect. Resveratrol may also have alexin-like activity for humans. Epidemiological, in vitro and animal studies suggest that a high resveretrol intake is associated with a reduced incidence of cardiovascular disease, and a reduced risk for cancer.

Resveratrol is found in grapevines (Vitis vinifera L). It occurs in the vines, roots, seeds and stalks, but its highest concentration is in grape skins. Wine also contains resveratrol. The concentration of resveratrol in red wine is much higher than that of white wine. The main difference between red and white wine production, besides the grapes used, is that for red wine the skins and seeds are involved in the process, while white wine is mainly prepared from the juice, essentially avoiding the use of grape skins and seeds. During the wine making process, resveratrol, as well as other polyphenols, including quercetin, catechins, gallocatechins, procyanidins and prodelphidins (condensed tannins), are extracted from the grape skins via a process called maceration.

Resveratrol, as well as the other polyphenols in wine, is thought to account in large part for the so-called French Paradox. The French Paradox—the finding that the rate of coronary heart disease mortality in France is lower than observed in other industrialized countries with a similar risk factor profile—has been attributed to frequent consumption of red wine.

In addition to grapes and wine, dietary sources of resveratrol include peanuts and mulberries. Resveratrol is also found in significant amounts in the dried roots and stems of the plant Polygonium cuspidatum Sieb. Et Zucc., also known as the Japanese knotweed. The dried root and stem of this plant is used in traditional Chinese and Japanese medicine as a circulatory tonic, among other things. This traditional Chinese and Japanese remedy is also known as Hu Zhang, Hu Chang, tiger cane, kojo-kon and hadori-kon. Most of the resveratrol-containing supplements which are marketed in the U.S. contain extracts of the root of Polygonium cuspidatum. Darakchasava, an ayurvedic herbal remedy, has as its principal ingredient Vitis vinifera L, and therefore, contains resveratrol. It is mainly used in ayurvedic medicine as a cardiotonic.

Resveratrol, which is also known as 3,4',5 trihydroxystilbene and 3,4',5-stilbenetriol, exists in cis- and trans-stereoisomeric forms. Resveratrol is the parent molecule of a family of polymers called viniferins. Cis- and trans-resveratrol occur naturally as do their glucosides. Resveratrol-3-O-beta-D-glucoside is also known as piceid, and the respective cis- and trans-glucosides are called cis-piceid and trans-piceid. The molecular formula of resveratrol is C14H12O3 and its molecular weight is 228.25 daltons. It is represented by the following structural formula:




Resveratrol

The stereoisomer of resveratrol found in grapes and peanuts is the trans-form. Both cis- and trans-resveratrol are found in Polygonium cuspidatum. Therefore, dietary supplements containing resveratrol, which are principally derived from this plant, contain both stereoisomers. The amount of resveratrol (trans-resveratrol) in peanuts ranges from 0.02 to 1.79 micrograms per gram. Red wine contains from 0.6 to 0.8 micrograms per milliliter, and fresh grape skin, approximately 50 to 100 micrograms per gram. A glass of red wine delivers on the average, between 600 to 700 micrograms of resveratrol.
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I hope this proves useful to you.
Take Care and God Bless !

Answer 2

a range of of places... a universal google can discover an excellent form of issues, yet examine that any innovations is from a respected source i.e. no longer a weblog or a talk talk board. seem for the web pages of nationwide institutions for regardless of subject matter you have an interest in. The 'literature' itself is often basically accessible through paid subscriptions or being a member of a specialist company, and besides, it regularly basically appears like non-experience because it really is written very technically. it truly is why it really is likely more desirable helpful to study those nationwide web pages because the files is offered more desirable in layman's words (and there stands out as the quite literature on a lot of those web pages too).

Answer 3

It is an extract from grape skins and is found in red wine. It works against cancer and fungus. There has been quite a bit of medical study on this. Some literature includes:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15498824
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12939617
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16461283
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15838800
http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/res_0224.shtml
http://cebp.aacrjournals.org/cgi/content/full/12/10/953