WHAT DOES PRIME MEAN IN 5 PRIME END OF RNA STRAND.?
2006-08-21 06:22:16 · 6 answers · asked by teru 1 in Science & Mathematics ➔ Other - Science
It refers to the numbering system of the carbon atoms in the ribose sugars of the RNA molecule. In a nucleotide, the atoms of the base are numbered in a particular way 1, 2, 3... and the atoms in the sugar are numbered 1', 2', 3' and so on. So, at one end of an RNA molecule the carbon atom that is not attached to another nucleotide is carbon number 5 of the ribose sugar (so, 5') and at the other end of the RNA, the HO- group attached to carbon number 3 of the sugar (3') is exposed.
2006-08-21 06:33:52 · answer #1 · answered by hcbiochem 7 · 0⤊ 0⤋
From wikipedia: In molecular biology, the best is used to indicate the positions of carbon on a hoop of deoxyribose or ribose. So in actuality, the three' bring about DNA/RNA is the top the place the 0.33 carbon has an hydroxyl team putting off it that may no longer linked to the subsequent base pair (because of the fact there is none). The 5' end has an phosphate putting off it no longer linked to the rest.
2016-12-14 09:19:40 · answer #2 · answered by Anonymous · 0⤊ 0⤋
RNA is a chain of nucleotides and those nucleotides have three parts: a phosphate, a base, and a pentose sugar (ribose in the case of RNA). Carbon atoms in the base are numbered starting at 1. Carbon atoms in the pentose sugar are numbered starting with 1'. So the prime refers to the ribose sugar part of the RNA molecule.
2006-08-21 10:58:48 · answer #3 · answered by Dr L 1 · 0⤊ 0⤋
It just refers to the directionality of the strand. The 3' end of a strand is so named due to it terminating at the hydroxyl (-OH) group of the third carbon in the sugar-ring, and is known as the tail end. The 5' end is named as the strand terminates at the chemical group attached to the fifth carbon in the sugar-ring.
Here's the wikipedia article on it:
http://en.wikipedia.org/wiki/3%27_end
2006-08-21 06:37:33 · answer #4 · answered by Anonymous · 0⤊ 0⤋
I'm no biochemist, but check out this band called "RNA"
They did a version of "Spanish Bombs" on the Surf Music Tribute to The Clash, a surf version of Rick James' "Super Freak" and a Mariachi version of Weezer's "Hashpipe" on other compilations.
http://www.CharlieDoesSurf.com/rna.htm
http://www.myspace.com/rickshawrecords
http://cordelia.stayfree.co.uk/Pages/Beyond%20the%20Sea.htm
2006-08-21 06:53:11 · answer #5 · answered by Rick W 5 · 0⤊ 0⤋
it ref. to -OH and COO- positions
2006-08-21 06:46:40 · answer #6 · answered by j_chiramel 2 · 0⤊ 0⤋