What happens during phagocytosis? What does the lysosome do here?

Question

Does the lysosome use high pressure to suck in wastes? Then low pressure to remove the reminants?

Or does it engulf the wastes at low pressure and then uses high pressure to remove the reminents?

I know the overal info about phagocytosis but can't find info about when the lysosome uses high or low pressure for input and output of wastes.
I've looked up this online for hours and have not been able to find information about this. So, so help would BE VERY MUCH APPRECIATED!

Thanks for the help.

Answer 1

Lysosomes....are totally what I do all day....

So...It's an interesting process and whats on here already isn't very clear....

Lysosomes are for degrading integral membrane proteins...
Not sure where your "pressure" hypothesis is coming from but it really has nothing to do with....

So integral membrane proteins...need to be degraded...
they get "ubiquitinated" which is the addition of the protein ubiquitin (just one of them) to the cytosolic portion of the integral membrane protein....

Before they go into lysosomes they first go to the "early endosome"

Here....ESCRT protein complexes recognize the ubiquitin on the protein and the protein buds inward forming an internal vesicle inside the endosome....

These vesicles accumlate and the endosome is now a "late endosome" which is also known as a multi-vesicular body or MVB

Heres the fun part...
The MVB either fuses with or matures into a lysosome....Inside the lysosome there are both proteases which chew up and degrade the protein as well as lipases which chew up and degrade the internal vesicles.....

The stuff in the previous answers about pH is correct....the early endome has a low pH...and as the endosomes mature the pH continues to drop....

The story is much more complicated (I know it sucks) but those are the basics

Good Luck with whatever...!!!

Answer 2

Lysosomes are uni-membraned organelles within a cell that contain lysozyme - hydrolytic compound that will degrade material brought in by engulfment. It uses a membrane potential gradient to maintain a lower pH (4.8) than the cytoplasm via a proton pump, thus there are more H+ inside than out. This acidic environment aids degradation of phagocytosed material. The inner surface of the lysosome has a glycoprotein mucus to protect it against autodigestion.

Answer 3

The lysosome only releases enzymes which would make the product easier to digest by the cell...during phagocytosis the cell has pseudopod, those ones would involve the product and get it into the cell producing a vesicle then the enzymes will destroy it or make it in small pieces so the cell can use it to have energy or produce new products itself.
I hope it is useful and clear..my language is Spanish