clamidia pneumoniae?

Question

Where can I find detail information of Clamidia pneumoniae? Is there a precise exam to determine the ailment? Is there a specific treatment for it?

Answer 1

Hi, chlamydia pneumoniae is small, gram-negative, obligate intracellular organism which causes mild pneumonia or bronchitis in adolescents and young adults. Older adults may experience more severe disease and repeated infections. there are two other members in the chlamydia family: Chlamydia psittaci, and Chlamydia trachomatis.

there are lab studies to determine the ailment, in this case, i take it you mean to diagnose that the pneumonia is caused indeed by chlamydia pneumonia:

1) One of the methods of diagnosing this bug is by checking for its antibody in the blood serum: a definite case of C pneumoniae infection occurs with a 4-fold rise in C pneumoniae–specific MIF antibody at 3-4 weeks. (Note: A CF test cross-reacts with C psittaci.)

2) another method is by looking at the serum immunoglobulin.

3)The absence of detectable antibodies several weeks after the onset of infection does not exclude a diagnosis of acute C pneumoniae pneumonia because the IgM antibody response may take as long as 6 weeks and the IgG antibody response may take as long as 8 weeks to appear in primary infections.

4) The white blood cell count is usually not elevated in C pneumoniae infection. Alkaline phosphate levels may be elevated.
In some laboratories, a polymerase chain reaction with pharyngeal swab, bronchoalveolar lavage, sputum, or tissue can be used to seek C pneumoniae–specific DNA. It is the most promising rapid test but is still experimental.

5)Cell culture with oropharyngeal swabs is probably the best test, but it requires specialized culture techniques. It is only performed in research laboratories

As for treatment: doxycycline is the treatment of choice except in children younger than 9 years and pregnant women. Treatment should be continued for at least 10-14 days after defervescence. If symptoms persist, a second course with a different class of antibiotics is usually effective.

Alternatives include erythromycin and newer macrolides such as azithromycin and clarithromycin. Newer macrolides are better tolerated than erythromycin. Shorter courses of the newer macrolides appear to be effective.

Telithromycin is the first antibiotic in a new class called ketolides and has been recently approved for use. however it is more expensive than doxycycline. Telithromycin is a potent inhibitor of CYP3A4 and can cause potentially dangerous increases in serum concentrations of simvastatin, lovastatin, atorvastatin, midazolam, and other drugs. If telithromycin is used, statins should be withheld for the duration of therapy.

Fluoroquinolones, including levofloxacin and gatifloxacin also have some activity, but it is less than that of tetracyclines or macrolides.

Hope this helps. :D

Answer 2

Chlamydia pneumoniae A species that is an important cause of pneumonia, bronchitis, and sinusitis. It is believed to be transmitted from person-to-person by respiratory tract secretions, such as droplets suspended in air. Most cases of respiratory infection are mild and rarely require hospitalization. It is possible that this organism is a factor in the development of coronary artery disease. Treatment consists of a daily tetracycline, macrolide, or fluoroquinolone for 14 to 21 days.

Answer 3

There is a wikipedia page devoted to it. The precise exam to determine the ailment will be a little difficult cos it can affect lungs, brain, heart, joints... so it will be depending on the patient rather than on the bug

Answer 4

try harmer's encyclopedia