In the process of signaling, what role do the T-tubules and sarcoplasmic reticulum play?

Answer 1

When the skeletal muscle receives the signal to contract from a motor nerve, the action potential starts at the neuromuscular junction and spreads along the surface of the muscle. To increase the speed with which the entire muscle contracts its actomyosin, since this is the goal of neural transmission to skeletal muscle, a system has developed to rapidly spread the signal of the action potential to the internal calcium stores that control actomyosin contraction.

The action potential passes along the membranes of the transverse (T-) tubules which are in very close proximity to a region of the sarcoplasmic reticulum in a structure known as the triad. Action potential depolarization in the T-tubules causes activation of the calcium release channels of the sarcoplasmic reticulum (SR), and calcium is moved into the sarcoplasm (cytoplasm) where it induces the contraction of the thick onto the thin filaments. At the end of the stimulus, calcium is pumped back into the SR via a different set of calcium channels and the actomyosin can relax, but is ready now to contract again.

Answer 2

WHOA! Thank you, I think this the first time in I don't know how long, when I have even understod what the heck someone's talking about. Truly, thank you. whooaaaa, dude.