Sorry, but I found three categories of drugs. It would not be wrong to consider one class as stimulants (Cocaine-Amphetamine) and the other opiates.
Illicit Drugs
Cocaine
Cocaine is either inhaled or injected as cocaine hydrochloride or smoked and inhaled in its free base form, which is better known as "crack" cocaine. The inhaled form may lead to sinus symptoms, epistaxis, and ulceration of the nasal septum, whereas complications of intravenous use include septic emboli and talc granulomatosis. However, inhaled crack cocaine produces the most significant and varied pulmonary complications. These are summarized in Table 33–5.
Most pulmonary complications of crack cocaine occur within 1–2 h of use, although patients may present up to 48–72 h after using the drug. Typical symptoms include cough, wheezing, shortness of breath, hemoptysis, chest pain, and carbonaceous sputum. Findings from physical examination correlate with the specific pulmonary complication (eg, rales with pulmonary edema and crepitus/subcutaneous emphysema with barotrauma). Electrocardiograms and chest radiographs are important in the evaluation of complications of cocaine abuse. Chest pain may be due to either cardiac complications such as ischemia, infarct, or dissection, pulmonary complications, or both. Similarly, pulmonary edema associated with cocaine use may be either cardiogenic (secondary to a cardiomyopathy or malignant hypertension) or noncardiogenic (due to direct toxic effects of the drug on the pulmonary epithelium).
Long-term sequelae of cocaine use have been difficult to study but include a mild reduction in DLCO, chronic pulmonary hemorrhage, pulmonary hypertension, and mild interstitial fibrosis.
Amphetamines
Methamphetamine is the most commonly abused amphetamine. It is known by a variety of street names including "ice,""crystal," and "crank." Pulmonary complications occur less frequently than with cocaine, but include bronchospasm, barotrauma, airway burns, pulmonary hypertension, granulomatosis, and noncardiogenic pulmonary edema.
Opiates
In addition to respiratory depression and septic emboli, opiates are associated with noncardiogenic pulmonary edema and talc granulomatosis. Noncardiogenic pulmonary edema occurs with morphine, fentanyl, and naloxone as well as heroine. Patients present with dyspnea, cough, and/or chest fullness. Chest radiographs reveal interstitial or, less commonly, alveolar edema. Treatment includes discontinuation of the drug and supportive measures.
Haim DY et al: The pulmonary complications of crack cocaine. A comprehensive review. Chest 1995;107:233. (Comprehensive review of the pharmacology of cocaine and pulmonary syndromes associated with crack cocaine.) [PMID: 7813284]
- TAKEN FROM CURRENT PULMONARY- FRANKEL
Chapter 33
Mc Graw-Hill Medical
AccessMedicine.com
2006-07-24 19:58:56
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answer #1
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answered by Expat Froggy 3
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Stimulants and depressants. If you're in college, you should know the effects.
2006-07-24 17:59:13
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answer #3
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answered by Anonymous
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natural and synthetic. Natural... mariguana (yes, mexicans write it mariguana not marijuana or marijane). And synthetic like extasy.
2006-07-24 18:01:45
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answer #5
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answered by Anonymous
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