What is mitochondrial mutations?

Question

More answers please.

Answer 1

Mitochondrial disorders are genetic disorders that are caused by mutations or changes in the mitochondrial DNA (mtDNA).

Diseases of the mitochondria appear to cause the most damage to cells of the brain, heart, liver, skeletal muscles, kidney and the endocrine and respiratory systems. Depending on which cells are affected, symptoms may include muscle weakness, loss of motor control, pain, GI (gut) disorders and swallowing difficulties, poor growth, cardiac disease, liver disease, diabetes, respiratory complications, seizures, visual/hearing problems, lactic acidosis, developmental delays and susceptibility to infection.

There are over 30 known mitochondrial disorders.

Answer 2

Mitochondria are the energy producing structures in cells. So if they were to mutate (or change), that would be a mitochondrial mutation...

I vaguely recall something from biology class about the evolution of cells. I think a scientific theory about the development of mitochondria is that they were originally single celled organisms that got enveloped into a cell structure, and then as a result of this mutually beneficial realtionship, eventually the organism was incorporated into part of the cell. Perhaps this is what the term refers to.

Answer 3

Mitochondria are little bodies inside a cell, and they have their own genetic material separate from the cell's genetic material. Just as mutations can occur in the cell's genetic material, they can occur in the mitochondrial genetic material. Incidentally, a baby inherits cellular genetic material half from the mother and half from the father; but since the ovum contains mitochondria and the sperm does not, (having been stripped of most of the cell parts to make it small enough to be a sperm) the baby inherits ALL its mitochondria from the mother. For whatever that's worth.

Answer 4

What ARE mitochondrial mutations? They're damaged areas in the DNA of mitochondria. Mitochondria have their own DNA separate from the nucleus of the cell, and due to the proximity to reactive oxygen radicals, mito DNA tends to accumulate damage more rapidly than nuclear DNA. Fortunately, when this happens, the cell can usually spit out the damaged mito and recover. However, inherited mutations are implicated in various myopathies such as Parkinson's.

Answer 5

Mitochondrial DNA is inherited thru mothers, so a mutation is an alteration of DNA, so tome it seems to mean , altered DNA that comes from the mothers' side of the family

Answer 6

it is a change in part in the cell called mitochondrial. Of cos this mitochondrial is controlling our gene code that define what we are.

Radiation subtances are the most likely external causes for this to happen.

Answer 7

where the mitochondria of the cell is messed up either by frameshift or point mutation! I think!

Answer 8

after many many generations, there are spontaneous mutations (carried by women, mother's of mother's of mother's etc) look at National Geographic website, there's a whole thing on it, under the Genographic Project, it's pretty cool: https://www3.nationalgeographic.com/genographic/

Answer 9

Sounds like an infection.

Answer 10

Can I tell you that I wish that I had never left school!!!???!!!