can anyone suggest an explanation for high optimum temperature for certain enzymes?

Question

well,usually optimum temperature for the enzymes is around 37-40 celcius..but enzyme x has optimum temperature as 45 celcius.can anyone suggest an explanation for this please??Thank you for your answer.I really appreciate that.Thanks a lot!!=)

Answer 1

Has to do with the kenetics of the enzyme.

I need you to be a bit more specific on the origin of the enzyme. For example, Taq polymerase is from Thermus aquaticus, a thermophyle bacterium that lives in extremely high temperatures. This is the organism's normal habitat.

If the enzyme is of human origin, this makes a difference. Some enzymes operate optimally during a fever or heatstroke to keep the major organs alive. Your immune cells typically function better at higher temperatures because of their specilized enzymes.

So it all depends. If you're looking for speculation on why this enzyme's kenetics work this way, just think a little bit. Is it a regulatory function? What would happen if this enzyme was "on" all the time? Could something bad come of it? What is the organism of origin? Does it typically function at that temperature? What do the stability data show when overlayed over the kinetics data? Is it less stable at lower temperatures even though the function is enhanced at higher temperatures? What is the cost to the cell for making this enzyme? Is it energetically efficient to produce? What about degredation? What else would be going on in that cell at that temperature? Does the kinetics data show any relation between binding and pH? How does this relate when looking at temperature?

Hope this helps!

Answer 2

Hi...
Ow, it`s a coincidence. I`ve just learned it 2 weeks ago in my school. OK there are several factors that could affect the rate of enzymes reaction. There are: temperature, PH (acidity), concentration (even it is the enzymes or the substrate). And now we are talking about the temperature. Yes it does. the enzymes optimum temperature is strongly related into the body temperature. Such we as the human have the optimum body temperature in 37 C. And so does our enzymes have the optimum temperature of 37 too. As decrease or increase the temperature from the optimum one, the protein that build up the enzymes us started to be unstable and denaturized. That is why yhe rate of treaction is decrease too .If we see the graph, it is look like a curve.

NB : Please notice me if there is a good and cheap human genetic university ok?

Answer 3

Malaniel : Greetings...
You didn't specify whether or not you were referring to animal or plant enzymes. The optimum temperature is very different for both! For instance, plant enzymes are very active in temperature ranges of 75 degrees to 122 degrees F.
While cooking foods over the optimum temperature of 118 degrees F, will kill all the usefu enzymes in the food, making the digestion of that particular food difficult!
Unfortunately for human digestion, pasterization of milk and other food stuffs is usually much higher than 118 degrees Farenheit!

Answer 4

The optimum temperature for enzymes depends on the enviorment in which they ussually have to work. Most our enzymes have optimal temperatue of around 37C because that's our normal body temperature. Plant enzymes have optimal temperature of around 25C. The enzymes of bacteria that lives in hot springs will have optimal temperature of 70-80C and so on.