Frame of reference in space time have a meaning?measurement are taken from a mass structure?

Question

The principle of relativety relates that no measurements can be taken from a non substance.

Answer 1

I am not sure I understand your question in the way it is phrased.

All measurements need to be taken in a reference frame...it is impossible not to.
Since there is no absolute coordinate system in the universe, every measurement is relative to the reference frame it is taken in.

For example,
lets say that you (meaning in YOUR reference frame) measured a space ship's velocity to be some value, v.
someone on the space ship on the other hand, who is in the Space Ships reference frame, would measure the speed of the ship to be zero and your speed to be v (in the opposite direction).
It does not make any sense to say that the space ship is traveling at a speed of v, since that leaves off the reference frame.

Ordinarily (under non relativistic conditions), the reference frame is assumed to be with respect to something at "rest".
For example, if you are in a car and look at the speedometer, it might read 55 mph. This speed obviously does not mean you are traveling at 55 mph with respect to the sun, mars, or alpha centauri, but rather with respect to the surface of the Earth.

It doesn't just apply for velocities either, it also would apply to distances, times, mass, momentum, energy, .....
In different reference frames, measurements can have all sorts of values, each just as "correct" as the next.

So for all measurements, a reference frame is required to make a measurement.