Why Acne Forms, and How Accutane Knocks It Out?

Answer 1

Several factors are known to be linked to acne:

Hormonal activity, such as menstrual cycles and puberty
Stress, through increased output of hormones from the adrenal (stress) glands.
Hyperactive sebaceous glands, secondary to the three hormone sources above.
Accumulation of dead skin cells.
Bacteria in the pores, to which the body becomes 'allergic'.
Skin irritation or scratching of any sort will activate inflammation.
Use of anabolic steroids.
Any medication containing halogens (iodides, chlorides, bromides), lithium, barbiturates, or androgens.
Exposure to high levels of chlorine compounds, particularly chlorinated dioxins, can cause severe, long-lasting acne, known as Chloracne.
Traditionally, attention has focused mostly on hormone-driven over-production of sebum as the main contributing factor of acne. More recently, more attention has been given to narrowing of the follicle channel as a second main contributing factor. Abnormal shedding of the cells lining the follicle, abnormal cell binding ("hyperkeratinization") within the follicle, and water retention in the skin (swelling the skin and so pressing the follicles shut) have all been put forward as mechanisms involved.

Several hormones have been linked to acne: the male hormones testosterone, dihydrotestosterone (DHT) and dehydroepiandrosterone sulfate (DHEAS), as well as insulin-like growth factor 1 (IGF-I). In addition, acne-prone skin has been shown to be insulin resistant.

Development of acne vulgaris in latter years is uncommon, although this is the age group for Rosacea which may have similar appearances. True acne vulgaris in older adults may be a feature of an underlying condition such as pregnancy and disorders such as polycystic ovary syndrome or the rare Cushing's syndrome.


IN TERMS OF ACCUTANE: READ THIS:
Accutane (or 13-cis retinoic acid), closely related to vitamin A, should be reserved for those with multiple, large, inflamed acne nodules, with evidence of scarring, who have not responded to appropriate combinations of conventional treatments. It may also be used in other situations at the discretion of your physician. This powerful, effective medication also has significant side effects.

The most devastating side effect does not apply to your son -- it occurs when a woman becomes pregnant while on Accutane. Accutane's effect on rapidly growing cells produces major abnormalities and deformations in unborn children. For this reason, two negative pregnancy tests must be obtained before beginning Accutane treatment for any woman. Women who are sexually active must use two forms of birth control. Avoiding pregnancy throughout the treatment course (and for one month afterwards) is of paramount importance. The typical treatment course with Accutane is 20 weeks.

Most people taking Accutane will experience dry skin, often resulting in nosebleeds, cracked lips, and irritated eyelids. For this reason, people taking Accutane usually have difficulty wearing contact lenses. Depression, fatigue, and musculoskeletal complaints are not uncommon. Accutane can also cause impaired night vision and increased sensitivity of the skin to the sun. One other major side effect is called pseudotumor cerebri -- the person behaves as if he or she had a brain tumor. Pseudotumor cerebri usually begins with a combination of headache and visual disturbance (blurred vision, double vision, or brief vision loss). There is often vomiting as well. There is no actual tumor, but the pressure inside the skull is increased. Accutane should be stopped immediately, since otherwise these children are at significant risk for permanent loss of vision. (Note: pseudotumor cerebri can also be caused by megadoses of vitamins.) Other rare side effects can occur. The prescribing physician or the pharmacy will usually distribute a handout of signs to watch out for while on Accutane.

For the right person, Accutane can make a powerful, positive difference. Be sure that the prescribing physician is well-versed in recognizing and managing the side effects of the drug. Blood tests (of liver enzymes and lipids) should be done to monitor side effects, both before beginning Accutane and then every 1 to 2 weeks, until the response to the drug is established. People taking Accutane should not take vitamin supplements containing vitamin A, or beta carotene, to avoid increased toxic effects. People taking Accutane cannot donate blood until they have been off the medicine for one month.

Answer 2

Try Acutane (America) or Roactutane (Australia). It will cure your acne but you will need a doctor or a dermatologist to prescribe you it. It does have some side effects like dry lips and hands and stuff. Just make sure you use a good moisturiser and sunscreen. I recommend Mary Kay's 30+ sunscreen - it's oil-free and won't break you out. BTW: do NOT use toothpaste. The fluoride in it can actually make your pimples worse.

Answer 3

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