2 positive HPT and next day 2 negative HPT?

Question

Got 2 positives at 10dpo and now 2 negatives at 11dpo, same brand Clearblue Digital. How can this be and what do I trust?

Answer 1

Maybe you are having a miscarriage. When you have a miscarriage, your pregnancy hormones drop. But, maybe you just got some bad tests. Go get a blood test from the doctor...they way more accurate!

Answer 2

Hey, I got a positive test but my period started anyway! Huh? Since some HPT's are so sensitive, they can detect a pregnancy in its very early stages. Unfortunately, it's estimated that up to 50% of pregnancies are lost very early on. In the past, most women did not even realize they were pregnant-- their periods would arrive on time, or perhaps a day or two late. Now, women testing very early may get a positive test, but experience bleeding almost immediately afterwards. This is an early miscarriage, also referred to as a "chemical pregnancy." It is likely that you did conceive and the embryo implanted for a short time before dying. This miscarriage is "disguised" as a period because the bleeding happens right around the time you would expect your period. Because this is so common, you probably have nothing to worry about, medically speaking, if it happens to you once or twice (although it is still heartbreaking when it happens!) If, however, this happens to you more than a couple times, or in consecutive pregnancies, you should discuss it with your doctor, as this can signal a problem (which can oftentimes be corrected with minimal treatment.)

That said, it is also possible to experience some spotting or bleeding and still have a healthy pregnancy, so don't panic! It may be implantation bleeding (from your baby snuggling in your uterus for a nice long stay!) If you experience bleeding after a positive pregnancy test, you should call your doctor.

In simple terms, the digital test stick sucks up urine like a "regular" HPT. The test has a control line like every other HPT, to indicate the test worked properly. Then there is a "results zone" where a second line may or may not appear. Here's the difference: the second line may appear even if you are not pregnant, because the antibodies in the "results zone" are NOT testing ONLY for pregnancy hormone. Drumroll please. The "results zone" detects not only hCG (pregnancy hormone) . . . but also LH (luteinizing hormone.) LH is found in women's bodies almost all the time in some quantitity. (See the Fertility Info section for the nitty-gritty.) So, depending upon where you are in your cycle, how much LH your body produces normally (which can be thrown off by conditions like PCOS), you may see a second line even when there is no hCG ("Not Pregnant.")

Next question: Why does this HPT detect LH as well as hCG? After all, the presence of LH (or lack thereof) has no bearing on pregnancy detection.

Well, the best I can do there is quote the patent itself: "The determination of the presence of more than two (is multiple) [sic] analytes in any sample may have significant clinical utility." (Then it cites some examples in tests for heart disease and diabetes.) It does not elaborate further on the hCG/LH connection . . . so, in light of the fact that Clearblue just came out with a (disposable) digital ovulation predictor kit, my guess is the technology is the same in both tests and the company can use interchangeable parts and have the same patent cover both products.

Last question: How does the digital reader know what the result is? Here's the patent again: "... a standard curve can be generated by running strips with samples with known concentrations of E-3-G BI [the antibody "cocktail" with the dye/antibodies that detect the hCG and LH]. The colour at the immobile zone can be read, for example using a Minolta chromameter, and the concentration of E-3-G calculated by extrapolating from the reflectance value." In other words, your pee reacts with the reagents, makes a line (or doesn't), and the digital holder reads the specific intensity/color of the line, NOT SIMPLY determining whether a second line exists. (A "chromameter" just measures the shades of various colors-- so when teeth-whitening products say they'll lighten your teeth "at least two shades," they're basing those measurements of shades on a chromameter's reading.)

To recap: most women will normally see 2 lines on the Clearblue Digital test, pregnant or not, simply because of the normal, average, boring presence of LH. Our naked eyes cannot determine the "shade" or "intensity" of the second line, meaning our naked eyes can't make heads or tails out of the result. When the display says "Not Pregnant," believe it, until proven otherwise. (Note: Clearblue publishes the sensitivity of the digital test at 50 mIU/mL, but when questioned on their 800 line, they say 25. e.p.t. Certainty publishes their sensitivity as 50 mIU/mL as well. See the HPT FAQ for more info on why different tests work at different times-- and also why it is possible to receive a negative result and still be pregnant.)

this came from the website http://www.peeonastick.com

A blood test would clear this all up. A blood test is 100 % accurate and it will show you are pregnant 6 days after conception.

Good luck

Answer 3

You either have a false positive or false negative. Call the number on the box or go to the free clinic, their tests are more accurate. Good luck :)