My first thought was metformin (glucophage). There seem to be several misconceptions about it, though. PCOS is very commonly linked to insulin resistance, which is not the same thing as diabetes, although it can lead to diabetes. Insulin resistance is a condition in which the cells of your body do not respond as well as they should to insulin, so glucose builds up in the body. To compensate for this, the pancreas secretes even more insulin in order to keep blood glucose levels in check. If this condition worsens, then the cells may continue losing the ability to respond to insulin until finally the pancreas is producing very high levels of insulin and is still not able to maintain stable blood glucose levels. That condition is a form of type 2 diabetes.
No one is quite sure how this contributes to PCOS, but it is thought that the high levels of insulin that we have in our bodies if we are insulin resistant can cause the ovaries to produce too many androgens (male hormones). This overabundance of male hormones causes many of the classic symptoms of PCOS, including infertility due to anovulation (lack of ovulation).
So, the reason that metformin can increase fertility in some women who have PCOS is that it is an insulin-regulating drug. In people with insulin resistance or type 2 diabetes, metformin reduces the amount of glucose that the body produces and increases the amount of glucose used by the cells. This means that less insulin is produced by the pancreas because glucose levels in the bloodstream are decreased. The decreased levels of insulin in the bloodstream can cause ovarian function to return to normal, which may include the return of ovulation. That's how it is thought that metformin can help women with PCOS get pregnant.
Don't be alarmed that metformin is categorized as a diabetes drug. It can be helpful even if you don't have diabetes, since most women with PCOS do have some degree of insulin resistance. While it is not actually a fertility drug, some women with PCOS are able to ovulate and have a regular cycle while taking metformin. If you become able to ovulate on a regular cycle, it should be much easier to get pregnant.
Check out www.soulcysters.net. It's a message board for women with PCOS and there are lots of women there who are TTC (trying to conceive).
2006-06-13 12:47:18
·
answer #1
·
answered by purplerose 4
·
3⤊
1⤋
The one thing SOOO many ppl don't understand about PCOS is the fact that SINCE our cycles aren't regular, using an ovulation predictor kit is nearly impossible since you'd have to test every day, several TIMES that day to see if you EVEN ovulated. It gets REALLY expensive. We're not like normal women that only have to use the kit one week out of the month. Try testing for 1,000 days in a row (I'm not making this up, either) & never ONCE testing positive for ovulation?
Also, Metformin or Glucophage (same drugs) are NOT fertility drugs!! They are a diabetes medication used to help control type II diabetes which often goest hand & hand w/women who have PCOS, since most women w/PCOS gain weight so easily & have a very difficult time taking it off & so develope type II diabetes.
Anyway, sorry, needed to get that out.
Your best bet, if you're not working w/one already, is to find a good OB/GYN who's gonna work w/you.
Btw, I have PCOS w/endometriosis, fun, I know LOL. Anyway, I've started taking Fertility Blend by Daily Wellness. I order it off of BabyCenter.com. I've heard some amazing stuff about it, especially that it helps make your cycles more regular so you CAN ovulate & better predict. I've only been taking it for a little over a month, so the jury is still out on it, but it was recomended by someone I know who took it to concieve. Also, it's curently undergoing clinical trials at Stanford University.
Best of luck to you!
I know that heartache you have. The one that never seems to go away & makes your arms ache even more for the baby you can't seem to have. I know all about the full heart & the empty arms. God do I know! I've been ttc for nearly 8yrs. I had a still born 7yrs ago & it took 6yr to concieve again & I lost that baby, too, just a yr ago.
*hugs*
2006-06-10 05:50:42
·
answer #2
·
answered by Wild Rose 4
·
0⤊
0⤋
I hardly ever had a period, like 1 or 2 a year. I really wanted a baby, so I went to my DR> and she did some tests to find out if I was insulin resistant. I was and I started taking Metformin and losing weight. Almost immediately I had a period every month!! About 10-12 months later I was pregnant. I now have two beautiful kids! I also have a friend who has PCOS and she had a lot of luck with Clomid the first time, the second time she didn't need anything at all! Ask your doctor to run tests-Metformin is a wonder drug for me! Good luck!!!
2006-06-12 06:13:17
·
answer #3
·
answered by sophiensamsmom 4
·
0⤊
0⤋
I have PCOS and my man has low count..We have been trying for 6 years with no luck. I am on metformin and was on clomid and still no luck! So we tried it with the Ovulation kit and it didn't work..So we had a IUI (artificial insem.) done and we still don't have kids..The DOC finally decided to put me on B/C pills to get me all straightened out and I have been on them for 6 months and this is my last pack, he seems to think that since I have been on B/C that now my menstrual will be back on track and we will have a better chance of conceiving...I don't know if u have tried any of these options that I have, but what doesn't work for 1 may always work for another..!!! GOOD LUCK!! I will let u know if I have any luck this month since the B/C pills!!
2006-06-11 04:40:34
·
answer #4
·
answered by LIL_A 1
·
0⤊
0⤋
Charting your cycles is step one (I also have PCOS). This is so, so important to anyone who is trying to conceive, trying to avoid conception, or just wants to have any clue at all what is happening with her own body.
If you don't conceive on your own after a year, even with charting, take your charts to your physician. Make sure this person is familiar with charting, though! Some docs discount it (for what reason, I have NO idea, maybe because they are clueless about it?).
My cycles are also very irregular and we are currently TTC #3. My cycles range anywhere from 29 to 90 days long, and I know when I'm fertile (when it's a good time to have sex to conceive) because I chart.
The other HUGE benefit to charting, especially to PCOS moms, is that when your midwife calculates your due date it will be based off of your period. For us PCOS moms, this is BAD!
If you ovulate on day 30, your due date will be off by as much as 2 weeks! If you ovulate even later, that will throw your date off that much more. So knowing exactly when you ovulated will give you a *for sure* due date.
2006-06-10 05:39:58
·
answer #5
·
answered by kriskruz 2
·
0⤊
0⤋
Take your time. I also have PCOS and have had it since I was 15. I am now 22 years old and pregnant with my second child. It takes a while to get pregnant if you don't see a doctor. It took three years to conceive my second child. Don't stress yourself out because it makes trying to conceive worse. But if you are hoping to have a child soon then you need to see an OB/GYN. They can help you determine the best time to try. And they may even help you with some fertility drugs. Good Luck and don't get stressed out if you don't conceive right away.
2006-06-10 04:57:36
·
answer #6
·
answered by I love my babies 4
·
0⤊
0⤋
With PCOS, usually the best choice is to see a reproductive endocronologist and get advice from him or her.
An OPK is relatively useless, BBT is completely useless...
Many women with PCOS do go on to become pregnant - sometimes they need a little help :-)
2006-06-10 08:02:02
·
answer #7
·
answered by IVF Expert 6
·
0⤊
0⤋
ask your doctor if you can try metformin, it helps to regulate periods. In fact, ask your doctor if he can do a test to make sure you are actually ovulating. If not, ask for chlomid or clomefine. Check out the links below :-)
P.S I did not say that metformin was a fertility drug. I said that it helps to regulate periods for women with PCOS. They are still running tests to see how effective it is.
2006-06-10 05:21:15
·
answer #8
·
answered by Anonymous
·
0⤊
0⤋
Start charting your body temp. And get an ovulation predictor. when your temp goes up and the ovulation predictor says your ovulating then try. Or go talk to an Ob/gyn and try to make a plan.
2006-06-10 04:45:50
·
answer #9
·
answered by Maw730 3
·
0⤊
0⤋
Start charting and just try to have sex every day after a period until the next period you get...Or at least every other day
2006-06-10 05:31:43
·
answer #10
·
answered by dnk0717 3
·
0⤊
0⤋