有高手可以幫我 回答解剖生理的問題可以嗎??詳細的...

Question

比較substrate-level phosphorylation和oxidative phosphorylation的不同?
並指出這兩者分別發生在glucose oxidation 的什麼stage ?

Answer 1

substrate-level phosphorylation is when you have two compounds (usually one phosphorylated compound and the other is ADP), one transfers its phophate group the other, catalyzed by enzymeeg.p=phospateA-p + B ---enzyme----> A + B-p (just a simple transfer of the phosphate group)in Glycolysis, substrate-level occurs twice in the pay-off phase (if you have a diagram you can see it clearly... i would scan if from my text but that takes too much work...)1) 1,3-bisphosphoglycerate + ADP ---phosphoglycerate kinase-----> 3-phosphoglycerate + ATP**1,3-bisphosphoglycerate can also be called 1,3-diphosphoglycerate...they are the same thing...**2) phosphoenolpyruvate + ADP ---pyruvate kinase---> pyruvate + ATPhere's an animation of glycolysis:http://www.northland.cc.mn.us/biology/Biology1111/animations/glycolysis.htmloxidative phosphorylation depends on the generation of H+ gradient across the inner mitochondion membrane.... then the ATP synthase uses the potential energy in the H+ gradient to drive the synthesis of ATPfirst, NADH is reduced to NAD+ donating electrons to the electron transport chain (a sequence of proteins that use the electrons to "pump out" H+ to create the H+ gradient), at the end of the chain, hydrogen and oxygen accepts the electrons to make waterhere's a diagram: http://www.gwu.edu/~mpb/oxidativephos.htmoxidative phosphorylation can occur (if there is no inhibition...) anytime when NADH or succinate is available

2006-03-23 13:36:18 補充：
i'm hoping you can understand it in english.. cos i can only explain it in english... ^^|||

2006-03-23 13:53:29 補充：
ah! found my mistake...
3rd last paragraph: first, NADH is "oxidized" to NAD+
(NOT REDUCED....)

2006-03-27 03:00:19 補充：
因為我在國外讀書~

2006-03-28 06:59:16 補充：
Pre-pharma系~ ㄏㄏ

Answer 2

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Answer 3

謝謝你~~這ㄍ我知道ㄌ
我需要ㄉ是~~
更多的~~~不同點~~詳細ㄉ~~

2006-03-25 17:23:33 補充：
我看ㄉ董~~不過為什ㄇ你要用英文寫ㄋ~~你是台灣人ㄇ

2006-03-27 19:10:26 補充：
mitochondion membrane.~~~~你拼錯囉!!少ㄌ一ㄍr~~~~呵呵～～
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2006-04-02 21:51:49 補充：
你是藥師？？

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Answer 4

substrate-level phosphorylation是不需要氧氣的反應, oxidative phosphorylation是需氧的反應且能產生更多的ATP供細胞使用